The Graduate Programme for In Vivo Pharmacology and Experimental Animals

  1. 2024
  2. Published

    Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction

    Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268

    Research output: Contribution to journalConference abstract in journalpeer-review

  3. Published

    Diet composition drives tissue-specific intensity of murine enteric infections

    Israelson, H., Vedsted-Jakobsen, Amalie, Zhu, L., Gagnaire, A., von Münchow, Alexandra, Polakovicova, N., Valente, Angela Hørdum, Raza, Ali, Andersen-Civil, A. I. S., Olsen, John Elmerdahl, Myhill, Laura Jessica, Geldhof, P. & Williams, Andrew Richard, 2024, In: mBio. 15, 2, 22 p., e0260323.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Effects of inhibition of Nav1.3, Nav1.7, and Nav1.8 channels on pain-related behavior in Speke's hinge-back tortoise (Kinixys spekii)

    Musembi Makau, Christopher, Towett, P. K., Kanui, T. I. & Abelson, Klas, 2024, In: Journal of Neuroscience Research. 102, 1, e25274.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Finding new analgesics: Computational pharmacology faces drug discovery challenges

    Barakat, Ahmed, Munro, G. & Heegaard, Anne-Marie, 2024, In: Biochemical Pharmacology. 222, 21 p., 116091.

    Research output: Contribution to journalReviewpeer-review

  6. Published

    Insulin-like growth factor 1 associated with altered immune responses in preterm infants and pigs

    Bæk, Ole, Rasmussen, Martin Bo, Gerts, T., Aunsholt, Lise, Zachariassen, G., Sangild, Per Torp & Nguyen, Duc Ninh, 2024, In: Pediatric Research. 95, p. 120–128 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Refinement of the motorised laminectomy-assisted rat spinal cord injury model by analgesic treatment

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2024, In: PLoS ONE. 19, 1 , 23 p., e0294720.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published
  9. 2023
  10. Published

    In vivo effect of rFVIII and rFVIIa in hemophilia A rats evaluated by the Tail Vein Transection Bleeding Model

    Stagaard, Rikke, Øvlisen, Gabi Overgaard, Klæbel, J. H., Danielsen, D., Lund, A., Elm, T. & Ley, C. D., 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1189-1199 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    An increased weaning age and liquid feed enhances weight gain compared to piglets fed dry feed pre-weaning

    Lyderik, Kimmie Kyed, Madsen, Johannes Gulmann, Larsen, Christina, Pedersen, M. L. M., Kjeldsen, N. J., Williams, Andrew Richard, Hedemann, M. S. & Williams, Charlotte Amdi, 2023, In: Animal. 17, 5, 100801.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Antinociceptive effects of nortriptyline and desipramine hydrochloride in Speke's hinge-back tortoise (Kinixys Spekii)

    Musembi Makau, Christopher, Towett, P. K., Kanui, T. I. & Abelson, Klas, 2023, In: Fundamental and Clinical Pharmacology. 37, 3, p. 567-576

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Bovine colostrum as a fortifier to human milk in very preterm infants – A randomized controlled trial (FortiColos)

    Ahnfeldt, Agnethe May, Aunsholt, Lise, Hansen, Bo Mølholm, Hoest, B., Jóhannsdóttir, V., Kappel, S. S., Klamer, A., Möller, S., Moeller, B. K., Sangild, Per Torp, Skovgaard, A. L., van Hall, Gerrit, Vibede, L. D. & Zachariassen, G., 2023, In: Clinical Nutrition. 42, 5, p. 773-783 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published
  15. Published

    Dietary non-starch polysaccharides impair immunity to enteric nematode infection

    Valente, Angela Hørdum, Jensen, K. M. R., Myhill, Laura Jessica, Zhu, L., Mentzel, Caroline M. Junker, Krych, Lukasz, Simonsen, H. T., Castro-Mejía, J. L., Gobbi, Alex, Bach Knudsen, K. E., Nielsen, Dennis Sandris, Thamsborg, Stig Milan & Williams, Andrew Richard, 2023, In: BMC Biology. 21, 16 p., 138.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published
  17. Published

    Dramatic increase in slaughter condemnations due to Escherichia coli ST23 and ST101 within the Danish broiler production

    Kromann, Sofie, Baig, S., Olsen, Rikke Heidemann, Edslev, S. M., Thoefner, Ida , Bojesen, Anders Miki, Jensen, Henrik Elvang & Stegger, M., 2023, In: Veterinary Microbiology. 280, 109696.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Effects of Weaning Age and Creep Feed Type on Growth Performance and Gut Maturation in Weaned Piglets

    Lyderik, Kimmie Kyed, Zhang, X., Larsen, Christina, Kjeldsen, N. J., Pedersen, M. L. M., Hedemann, M. S., Williams, Andrew Richard, Williams, Charlotte Amdi & Madsen, Johannes Gulmann, 2023, In: Animals. 13, 11, 1851.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Establishment and application of an aerogenous model of avian colibacillosis

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Thoefner, Ida & Jensen, Henrik Elvang, 2023.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  20. Published
  21. Published

    Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology

    Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Hair glucocorticoids are not a historical marker of stress: Exploring the time-scale of corticosterone incorporation into hairs in a rat model

    Colding-Jørgensen, Pernille, Hestehave, S., Abelson, Klas & Kalliokoski, Otto, 2023, In: General and Comparative Endocrinology. 341, 11 p., 114335.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published
  24. Accepted/In press

    Influence of general anaesthesia on circulating biomarkers of glucose metabolism in pigs

    Christoffersen, B., Bundgaard, C. J., Hjøllund, K. R., Fels, J. J., Boll, K. K., Lyhne, Mille Kronborg & Olsen, Lisbeth Høier, 2023, (Accepted/In press) In: Laboratory Animals.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs

    Christiansen, Line Iadsatian, Holmqvist, B., Pan, X., Holgersen, K., Lindholm, S. E. H., Henriksen, Nicole Lind, Burrin, D. G., Ley, D., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: eNeuro. 10, 4, ENEURO.0430-22.2023.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs

    Christiansen, Line Iadsatian, Ventura, G. C., Holmqvist, B., Aasmul-Olsen, Karoline, Lindholm, S. E. H., Lycas, M. D., Mori, Yuki, Secher, Jan Bojsen-Møller, Burrin, D. G., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: Frontiers in Neuroscience. 17, 15 p., 1205819.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published
  28. Published

    Neonatal prophylactic antibiotics after preterm birth affect plasma proteome and immune development in pigs

    Muk, T., Leto, A., Brunse, Anders, Stensballe, A., Thymann, Thomas, Sangild, Per Torp & Nguyen, Duc Ninh, 2023, In: Pediatric Research. 94, p. 530–538

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response

    Reimann, Maria Josefine, Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, Signe Emilie, Møller, J. E., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Internal Medicine. 37, 6, p. 1947-2660

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs

    Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33-33 1 p., O11.

    Research output: Contribution to journalConference abstract in journal

  31. Published

    Pharmacological safety of dimethoxy curcumin-human serum albumin conjugate for potential therapeutic purpose

    Korah, M. C., Sreelatha, Harikrishnan Vijayakumar, Deepa, S., Arya, A., Sabareeswaran, A., Mohanan, P. V. & Krishnan, L. K., 2023, In: Canadian Journal of Physiology and Pharmacology. 101, 6, p. 304-315

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Rethinking data treatment: The sucrose preference threshold for anhedonia in stress-induced rat models of depression

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2023, In: Journal of Neuroscience Methods. 395, 11 p., 109910.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

    Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Transplantation of fecal filtrate to neonatal pigs reduces post-weaning diarrhea: A pilot study

    Larsen, Christina, Andersen, Amanda Bastian, Sato, Helena, Brunse, Anders & Thymann, Thomas, 2023, In: Frontiers in Veterinary Science. 10, 1110128.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Ultra-High Temperature Treatment of Liquid Infant Formula, Systemic Immunity, and Kidney Development in Preterm Neonates

    Sun, Jing, Akıllıoğlu, H. G., Zhong, Jingren, Muk, T., Pan, X., Lund, Marianne N., Sangild, Per Torp, Nguyen, Duc Ninh & Bering, Stine Brandt, 2023, In: Molecular Nutrition and Food Research. 67, 24, 12 p., 2300318.

    Research output: Contribution to journalJournal articlepeer-review

  36. E-pub ahead of print

    Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

    Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2023, (E-pub ahead of print) In: Laboratory Animals.

    Research output: Contribution to journalJournal articlepeer-review

  37. 2022
  38. Published

    Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model

    Berke, M. S., Fensholdt, L. K. D., Hestehave, S., Kalliokoski, Otto & Abelson, Klas, Jan 2022, In: PLoS ONE. 17, 1, 21 p., e0260356.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    In vivo models of Escherichia coli infection in poultry

    Kromann, Sofie & Jensen, Henrik Elvang, 2022, In: Acta Veterinaria Scandinavica. 64, 33.

    Research output: Contribution to journalReviewpeer-review

  40. Published

    A Randomized, Controlled Study to Investigate How Bovine Colostrum Fortification of Human Milk Affects Bowel Habits in Preterm Infants (FortiColos Study)

    Kappel, S. S., Sangild, Per Torp, Ahnfeldt, Agnethe May, Johannsdottir, V., Soernsen, L. J., Bak, L. B., Friborg, C., Moller, S., Zachariassen, G. & Aunsholt, Lise, 2022, In: Nutrients. 14, 22, 14 p., 4756.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study

    Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Anti-protozoal activity and metabolomic analyses of Cichorium intybus L. against Trypanosoma cruzi

    Peña-Espinoza, M., Romero-Uzqueda, Y., Valente, Angela Hørdum, de Roode, M., Simonsen, H. T., Thamsborg, Stig Milan, Williams, Andrew Richard & López-Muñoz, R., 2022, In: International Journal for Parasitology: Drugs and Drug Resistance. 20, p. 43-53 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published
  44. Published

    Bodyweight, locomotion, and behavioral responses in the naked mole-rat (heterocephalus glaber) after lipopolysaccharide administration

    Kisipan, Mosiany Letura, Ojoo, R. O., Kanui, T. I. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 191-191 PE21.

    Research output: Contribution to journalConference abstract in journalpeer-review

  45. Published

    Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets

    Henriksen, Nicole Lind, Asmussen, K. S., Pan, X., Jiang, Pingping, Mori, Yuki, Christiansen, Line Iadsatian, Sprenger, R. R., Ejsing, C. S., Pankratova, Stanislava & Thymann, Thomas, 2022, In: Scientific Reports. 12, 1, 3303.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    CTLA4-Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats

    Øvlisen, Gabi Overgaard, Thygesen, P., Weldingh, K. N., Bloem, E., Skov, Søren, Almholt, K., Lövgren, K. M., Ley, C. D. & Holm, T. L., 2022, In: Haemophilia. 28, 4, p. 568-577

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Clinical outcome and gut development after insulin-like growth factor-1 supplementation to preterm pigs

    Holgersen, K., Rasmussen, Martin Bo, Carey, G., Burrin, D. G., Thymann, Thomas & Sangild, Per Torp, 2022, In: Frontiers in Pediatrics. 10, 868911.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Colibacillosis in poultry: Aetiology, pathogenesis, diagnosis, and control

    Kromann, Sofie, 2022, University of Copenhagen.

    Research output: Book/ReportPh.D. thesis

  49. Published

    Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs

    Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Donor-dependent fecal microbiota transplantation efficacy against necrotizing enterocolitis in preterm pigs

    Hui, Yan, Vestergaard, G., Deng, Ling, Kot, Witold, Thymann, Thomas, Brunse, Anders & Nielsen, Dennis Sandris, 2022, In: npj Biofilms and Microbiomes. 8, 1, 12 p., 48.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Effect of the sodium-glucose cotransporter-2 inhibitor dapagliflozinon platelet aggregation response in Cavalier King Charles Spanielswith and without cardiac disease

    Speitzer, A., Øgelund, E., Reimann, Maria Josefine, Møller, J. E., Skovsted, G. F., Lyhne, Mille Kronborg, Verma, S., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 2473 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  52. Published

    Effects of Transdermal Fentanyl Treatment on Acute Pain and Inflammation in Rats with Adjuvant-induced Monoarthritis

    Berke, M. S., Colding-Jørgensen, Pernille, Pedersen, L. G., Hestehave, S., Kalliokoski, Otto, Jensen, Henrik Elvang, Sørensen, Dorte Bratbo, Hau, Jann & Abelson, Klas, 2022, In: Comparative Medicine. 72, 5, p. 320–329

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Effects of anti-inflammatory drugs on induced chronic Inflammation in the naked mole rat

    Thuo, Jesse Kevin Ndung´u, Towett, P., Kanui, T. I. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 131-132 PA24.

    Research output: Contribution to journalConference abstract in journalpeer-review

  54. Published

    Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

    Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Electrocardiography and heart rate variability in Göttingen Minipigs: Impact of diurnal variation, lead placement, repeatability and streptozotocin-induced diabetes

    Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Helgogaard, T., Vegge, A., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 107221.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Fecal filtrate transplantation protects against necrotizing enterocolitis

    Brunse, Anders, Deng, Ling, Pan, X., Hui, Yan, Castro Mejia, J. L., Kot, Witold, Nguyen, Duc Ninh, Secher, Jan Bojsen-Møller, Nielsen, Dennis Sandris & Thymann, Thomas, 2022, In: The ISME Journal. 16, p. 686–694

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Fibrous dysplasia animal models: A systematic review

    Hopkins, Chelsea, de Castro, L. F., Corsi, A., Boyce, A., Collins, M. T., Riminucci, M. & Heegaard, Anne-Marie, 2022, In: Bone. 155, 13 p., 116270.

    Research output: Contribution to journalReviewpeer-review

  58. Published

    Glucose supply and glycolysis inhibition shape the clinical fate of Staphylococcus epidermidis-infected preterm newborns

    Muk (Mudi), T., Brunse, Anders, Henriksen, Nicole Lind, Aasmul-Olsen, Karoline & Nguyen, Duc Ninh, 2022, In: JCI Insight. 7, 11, 18 p., e157234.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function

    Voetmann, Louise Marie, Underwood, C. R., Rolin, B., Hansen, Axel Kornerup, Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Is sweet consumption under thirst and hunger really a good indicatior or depression?

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hestehave, S., 2022, In: Laboratory Animals. 56, S1, p. 25-26 S2A5.4.

    Research output: Contribution to journalConference abstract in journalpeer-review

  61. Published
  62. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Modulation of nociception by noradrenaline and serotonin receptor systems in speke’s hinge-back tortoise

    Musembi Makau, Christopher & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 128-129 PA15.

    Research output: Contribution to journalConference abstract in journalpeer-review

  64. Published

    Modulation of nociception by tricyclic antidepressants in the Speke’s hinge-back tortoise

    Musembi Makau, Christopher, 2022, Canadian Society for Brain, Behaviour, and Cognitive Science: CBBCS 2022 - 32nd Annual Meeting in Halifax, Nova Scotia. Halifax, Canada, p. 44-44

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

  65. Published

    My journey towards higher education in laboratory animal science - a big thanks to European teaching and Laboratory Animals Limited (LAL) funding!

    Sreelatha, Harikrishnan Vijayakumar, 2022, In: Laboratory Animals. 56, 5, p. 491-492

    Research output: Contribution to journalComment/debatepeer-review

  66. Published

    Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir

    Pedersen, K., Gradel, Anna Katrina Jógvansdóttir, Ludvigsen, T. P., Christoffersen, B. Ø., Fuglsang-Damgaard, C. A., Bendtsen, K. M., Madsen, S. H., Manfé, V. & Refsgaard, H. H. F., 2022, In: Translational Research. 239, p. 71-84

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Perioperative nivolumab monotherapy versus nivolumab plus ipilimumab in resectable hepatocellular carcinoma: a randomised, open-label, phase 2 trial

    Kaseb, A. O., Hasanov, E., Cao, H. S. T., Xiao, L., Vauthey, J. N., Lee, S. S., Yavuz, B. G., Mohamed, Y. I., Qayyum, A., Jindal, S., Duan, F., Basu, S., Yadav, S. S., Nicholas, C., Sun, J. J., Singh Raghav, K. P., Rashid, A., Carter, K., Chun, Y. S., Tzeng, C. W. D. & 9 others, Sakamuri, D., Xu, L., Sun, R., Cristini, V., Beretta, L., Yao, J. C., Wolff, R. A., Allison, J. P. & Sharma, P., 2022, In: The Lancet Gastroenterology and Hepatology. 7, 3, p. 208-218 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Refinement of the rat contusion model of thoracic spinal cord injury

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 27-27 S2B3.1.

    Research output: Contribution to journalConference abstract in journalpeer-review

  69. Published

    Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation

    Jensen, Ditte Marie, Skovsted, Gry Freja, Bonde, M. F. B., Bentzon, J. F., Rolin, B., Franck, G., Ougaard, M. K. E., Voetmann, Louise Marie, Bachmann, J. C., Uryga, A., Pyke, C., Kirk, R. K., Hvid, H., Knudsen, L. B., Lykkesfeldt, Jens & Nyberg, M., 2022, In: Atherosclerosis Plus. 49, p. 32-41 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Suckling Induces Differential Gut Enzyme Activity and Body Composition Compared to Feeding Milk Replacer in Piglets

    Williams, Charlotte Amdi, Pedersen, M. L. M., Larsen, Christina, Klaaborg, J., Williams, Andrew Richard & Madsen, Johannes Gulmann, 2022, In: Animals. 12, 22, 3112.

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain

    Zhang, X. Y., Barakat, Ahmed, Diaz-delCastillo, M., Vollert, J., Sena, E. S., Heegaard, Anne-Marie, Rice, A. S. C. & Soliman, N., 2022, In: Pain. 163, 11, p. 2076-2102

    Research output: Contribution to journalReviewpeer-review

  72. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Ultra-High Temperature Treatment and Storage of Infant Formula Induces Dietary Protein Modifications, Gut Dysfunction, and Inflammation in Preterm Pigs

    Sun, Jing, Akıllıoğlu, H. G., Aasmul-Olsen, Karoline, Ye, Y., Lund, P., Zhao, X., Brunse, Anders, Nielsen, C. F., Chatterton, Dereck Edward Winston, Sangild, Per Torp, Lund, Marianne N. & Bering, Stine Brandt, 2022, In: Molecular Nutrition & Food Research. 66, 20, 13 p., 2200132.

    Research output: Contribution to journalJournal articlepeer-review

  74. Published
  75. Published

    Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig

    Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    We need to talk about fraudulent animal studies: learnings from a systematic review

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2022, In: Laboratory Animals. 56, S1, p. 172-172 PD15.

    Research output: Contribution to journalConference abstract in journalpeer-review

  77. 2021
  78. Published

    High Parenteral Support Volume Is Associated With Reduced Quality of Life Determined by the Short‐Bowel Syndrome Quality of Life Scale in Nonmalignant Intestinal Failure Patients

    Nordsten, C. B., Mølsted, Stig, Bangsgaard, L., Fuglsang, K. A., Brandt, C. F., Niemann, Mads Jacob & Jeppesen, Palle Bekker, 1 Jul 2021, In: Journal of Parenteral and Enteral Nutrition. 45, 5, p. 926-932 7 p.

    Research output: Contribution to journalLetterpeer-review

  79. Published

    A reduced CP level without medicinal zinc oxide does not alter the intestinal morphology in weaned pigs 24 days post-weaning

    Larsen, Christina, Lynegaard, J. C., Pedersen, Anni Øyan, Kjeldsen, N. J., Hansen, C. F., Nielsen, Jens Peter & Williams, Charlotte Amdi, 2021, In: Animal. 15, 4, 100188.

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    A report on less-severe, long-duration persistent hind-limb ischemia surgical rabbit model

    Sreelatha, Harikrishnan Vijayakumar, Shenoy, S. J., Ranaraj, V. R., Sukhija, S. & Oloyo, A. K., 2021, In: Journal of the Hellenic Veterinary Medical Society. 72, 4, p. 3455-3462 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  81. Published

    Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree

    Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

    Lindenberg, F. C., Lützhøft, Ditte Olsen, Krych, Lukasz, Fielden, J., Kot, Witold, Frøkiær, Hanne, van Galen, G., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Frontiers in Microbiology. 12, 666039.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels

    Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

    Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, Stine Brandt & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Decreased expression of the GLP-1 receptor after segmental artery injury in mice

    Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

    Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    Development of an aerogenous Escherichia coli infection model in adult broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Scientific Reports. 11, 15 p., 19556.

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis

    Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published
  90. Published

    Extracellular vesicles as drivers of non-alcoholic fatty liver disease: Small particles with big impact

    Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 1, p. 1-13 13 p., 93.

    Research output: Contribution to journalReviewpeer-review

  91. Published

    Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Porsgaard, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 6, p. 783-794

    Research output: Contribution to journalJournal articlepeer-review

  92. Published
  93. Published

    Hyperinsulinaemic hypoglycaemia in non-anaesthetized Göttingen minipigs induces a counter-regulatory endocrine response and electrocardiographic changes

    Lyhne, Mille Kronborg, Vegge, A., Povlsen, G. K., Slaaby, R., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2021, In: Scientific Reports. 11, 11 p., 5983.

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    Identification of compounds responsible for the anthelmintic effects of chicory (Cichorium intybus) by molecular networking and bio-guided fractionation

    Valente, Angela Hørdum, de Roode, M., Ernst, M., Peña-Espinoza, M., Bornancin, L., Bonde, C. S., Martínez-Valladares, M., Ramünke, S., Krücken, J., Simonsen, H. T., Thamsborg, Stig Milan & Williams, Andrew Richard, 2021, In: International Journal for Parasitology: Drugs and Drug Resistance. 15, p. 105-114 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  95. Published

    Infant Formula Based on Milk Fat Affects Immune Development in Both Normal Birthweight and Fetal Growth Restricted Neonatal Piglets

    Bæk, Ole, Asmussen, K. S., Muk (Mudi), T., Williams, Charlotte Amdi, Heegard, P., Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Nutrients. 13, 10, 3310.

    Research output: Contribution to journalJournal articlepeer-review

  96. Published

    Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD

    Jensen, Victoria Svop, Fledelius, C., Zachodnik, C., Damgaard, J., Nygaard, H., Tornqvist, K. S., Kirk, R. K., Viuff, B. M., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Journal of Translational Medicine. 19, 1, 80.

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

    Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

    Research output: Contribution to journalJournal articlepeer-review

  98. Published

    Milk osteopontin for gut, immunity and brain development in preterm pigs

    Aasmul-Olsen, Karoline, Henriksen, Nicole Lind, Nguyen, Duc Ninh, Heckmann, A. B., Thymann, Thomas, Sangild, Per Torp & Bering, Stine Brandt, 2021, In: Nutrients. 13, 8, 2675.

    Research output: Contribution to journalJournal articlepeer-review

  99. Published
  100. Published

    Modulation of nociception by amitriptyline hydrochloride in the Speke’s hinge-back tortoise (Kiniskys spekii)

    Musembi Makau, Christopher, Towett, P. K., Abelson, Klas & Kanui, T. I., 2021, In: Veterinary Medicine and Science. 7, 3, p. 1034-1041

    Research output: Contribution to journalJournal articlepeer-review

  101. Published
  102. Published

    Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

    Research output: Contribution to journalJournal articlepeer-review

  103. Published
  104. Published

    Refinement of the spinal cord injury rat model and validation of its applicability as a model for memory loss and chronic pain

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2021, In: Heliyon. 7, 7, 11 p., e07500.

    Research output: Contribution to journalJournal articlepeer-review

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