PhD Project List – University of Copenhagen

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Project TitlePhD StudentDepartmentPrincipal SupervisorStart of Study
46 The involvment of the noradrenergic receptor system in an-tinociceptive mechanisms in the naked mole rat (Heterocepha-lus Glaber) Royford Murangiri Mwobobia Dept. of Experimental Medicine Klas Abelson 01.12.2017
45 Nutrition effects on immunity development in newborns Ole Bæk Dept. of Veterinary and Animal Sciences Per Torp Sangild 01.09.2017
44 Empirical study of bias in a rat model of rheumatoid arthritis Dasa Seveljevic-Jaran Dept. of experimental medicine Jan Hau 01.12.2015
43 Effects of GLP-1 on atherosclerosis, vascular functionality and remodelling Katrine Dahl  Bjørnholm Dept. of Veterinary Animal Sciences Jens Lykkesfeldt 01.04.2017
42 Investigating the role of GLP-1 receptor activation in the gastropyloric region for stimulating intestical mucosal defence and decreasing intestinal permeability Louise Pedersen Dept. of Veterinary Animal Sciences Axel Kornerup Hansen 01.03.2017
41 Refinement of a rat model of inflammatory pain and arthritis Mie Schou Berke Dept. of experimental medicine Klas Abelson 01.02.2017
40 Mechanisms of carbon nanotube-induced mesothelioma Regitze Sølling Wils Dept. of Public Health Peter Møller 01.02.2017
39 Early feeding and brain development in preterm pigs Charlotte Holme Nielsen Dept. of Vet. Clinical and Animal Sciences Thomas Thymann 01.01.2017
38 Parasites and plants-exploring the anti-parasitic activity of a bioactive livestock forage Angela Hørdum Valente Veteriniary Parasitology Stig Milan Thamsborg 01.12.2016
37 Role of the PACAP system in a novel inflammatory rat model for headache: Effect on cAMP and Ca2+ signalling pathways and selected potential targets for headache therapy Simona Denise Frederiksen Clinical Experimental Research, Glostrup Research inst. Lars Edvinsson 01.12.2016
36 Refinement of the contusive spinal cord injury rat model Harikrishnan Vijayakumar Sreelatha Division of Laboratory Animal Science, India Klas Abelson 01.12.2016
35 Investigating the role of FGF21 on hepatic oxidative stress and NALFD/NASH Julie Hviid Klæbel Dept. of Veterinary Disease Biology Jens Lykkesfeldt 01.10.2016
34 Immunity development in preterm newborns Ren Shuqiang Vet. clinical and animal sciences Per Torp Sangild 01.10.2016
33 The continuous performance test (CPT) to study attentional performance: in vivo pharmacological and optogenetic studies in mice, and human stidies in healthy volunteers Maitane Caballero Puntiverio Drug Design and Pharmacology Jesper Tobias Andreasen 01.09.2016
32 Effects of insulin treatment on NAFLD in diabetic rodents Victoria Svop Jensen Dept. of Veterinary Disease Biology/Novo Nordisk Jens Lykkesfeldt 01.09.2016
31 In vivo characterization of critical determinants of bleeding in the development of harmophilic artropathy in the F8-KO rat Kåre Kryger Vøls Dept. of Veterinary Disease Biology/Novo Nordisk Axel Kornerup Hansen 01.08.2016
30 Factors driving the variation in absorption of subcutaneously administered insulins Anna Katrina Jógvansdóttir Gradel Dept. of Veterinary Disease Biology/Novo Nordisk Jens Lykkesfeldt 01.03.2016
29 The effect of diet-induced obesity on differential metabolic responses in rats and mice Hannah Louise Zakariassen Dept. of Veterinary Disease Biology/Novo Nordisk Jens Lykkesfeldt 01.03.2016
28 Nanoparticles and effects on male reproductive function Astrid Skovmand Dept. of Large Animal Sciences Sandra Goericke-Pesch 01.01.2016
27 Dietary and microbial influence on gut and brain in early Karina Ryom Dept. of veterinary clinical and animal sciences Thomas Thymann 01.01.2016
26 Development of novel models reflecting human fatty liver disease and nonalcoholic steatohepatitis Kirstine Sloth Tølbøl Dept. of biomedical sciences Ole Hartvig Mortensen 01.02.2016
25 Characterization of immune complex formation and elimination following administration of human antibodies to rats Lykke Boysen Dept. of Veterinary Disease Biology Jens Lykkesfeldt 01.11.2015
24 Transscriptomic analysis of the trigeminovascular system after glyceryl trinitrate infusion in rat. Rikke Elgaard Christensen Dept. of Clinical Medicine Jes Olesen 01.11.2015
23 Unraveling disease mechanisms inthe diabetic heart Simone Krog Christensen Dept. of Vet. Disease Biology (IVS) Lisbeth Høier Olsen 01.10.2015
22 The role of the nociceptin/orhaninFQ system in an animal model of bone cancer pain Sonny Harmanus Johannes Sliepen Dept. of drug design and pharmacology Anne-Marie Heegaard 01.10.2015
21

Animal models for examining the role of osteoclasts in osteoarthritis pain

Anna Katri Dept. of drug design and pharmacology Anne-Marie Heegaard 23.09.2015
20

A novel animal model of metabolic bone pain

Marta Díaz del Castillo Dept. of Drug Design and Pharmacology Anne-Marie Heegaard 01.08.2015
19

Effect of prebiotics/probiotics on brain development in preterm pig

Jing Sun Vet. Clinical and Animal Sciences Per Torp Sangild 01.10.2014

18

Characterization of murine experimental models of diabetic nephropathy

Maria Katarina Elm Ougaard Dept. of Vet. Disease Biology (IVS) Henrik Elvang 01.06.2015

17

Refining humane endpoints of long term studies:Using murine species-specific behaviours to assess reduced welfre in the home cage of mice and rats

Karen Gjendal Dept. of Vet. Disease Biology (IVS) Dorte Bratbo 01.05.2015

16

The preterm piglet as a spontaneous model hypoxic-inflammatory  model of premature brain injury

Anders Brunse IKVH Per Torp Sangild 01.10.2014

15

Refinement of animal models in pain research - a study of the comorbidity between pain, anxiety and depression in various rat strains, for the improvement of the translation from animals to humans

Sara Hestehave Kristensen Dept. of experimental medicin Klas Abelson 02.03.2015

14

Characterization of the natriuretic peptide system in a

dietinduced obese atherosclerotic minipig model”

Camilla Schumacher-Petersen Dept. of Vet. Disease Biology (IVS)/Novo Nordisk Lisbeth Høier Olsen 01.03.2015
13

Mechanisms of neuronal damage induced by vitamin C de-ficiency

Stine Normann Hansen Dept. of Vet. Disease Biology (IVS) Jens Lykkesfeldt 01.02.2015
12

Kinase inhibition for alleviating cancer-induced bone pain

Camilla Kristine Appel Dept of Drug Design & Pharmacology Anne-Marie Heegaard 15.01 2015
11

Bioethical improvements in the collagen induced arthritis (CIA) model

Sisse Clausen Nørgaard Dept. of Vet. Disease Biology (IVS)/Novo Nordisk Dorte Bratbo Sørensen 15.09.2014
10

Characterization of diabetic nephropathy in a minipig model of dyslipidemia, hyperglycemia and hypertension

Rikke Lindgaard Thomsen Dept. of Vet. Disease Biology (IVS)/Novo Nordisk Lisbeth Høier Olsen 01.09.2014
9

The impact of neonatal Fc receptor and disease processes on in vivo distribution of biopharmaceuticals using advanced imaging technologies

Laura Kofoed Hvidsten Ørstrup Dept. of Vet. Disease Biology (IVS)/Novo Nordisk Jens Lykkesfeldt 01.05.2014
8

Characterization of the in vivo response to antifibrinolyticintervention in haemophilia  A”

Rikke Stagaard Knudsen Dept. of Vet. Disease Biology (IVS)/Novo Nordisk Lisbeth Høier Olsen 01.03.2014
7

Experimental model for treatment of retinal detachment involving fovea:aspects of function and treatment 

Nina Buus Sørensen Clinial medicine/SUND Jens Folke Kiilgaard 01.03.2014
6

In vivo regulatio nof vitamin C transport in the brain during deficiency

Maiken Marie Lindblad Dept. of Vet. Disease Biology (IVS Pernille Tveden-Nyborg 01.11.2013
5

The specificity of regulator cells in relation to Type 1 diabetes

Pernille Kihl Dept. of Vet. Disease Biology (IVS)/Novo Nordisk Axel Kornerup Hansen 01.06.2013
4

Systemic oxidative stress and vascular dysfunction by oral exposure to particles

Ditte Marie Jensen Public Health/SUND Peter Møller 01.06.2013
3

 Automated repeated blood sampling for the study of stress hormone dynamics combined with behavioral studies and pathology in permanently catheterized laboratory mice

Anne Charlotte Teilmann Exp. med./SUND Klas S.P. Abelson 01.02.2013
2

Optimization of dosage and cliinical efficacy of new macrolides

Astrid K. Larberg Dept. of Vet. Disease Biology (IVS)/SUND Christian Friis 01.01.2013
1 Evaluation of new in vivo cardiovascular biomarkers in an animal model of chronic mitral regurgitation Maria Reimann Dept. of Vet. Disease Biology (IVS)/SUND Lisbeth Høier Olsen 01.04.2012












PhD Defences 2017

Pernille Kristensen defended her thesis on 10 April 2017.

Simon Haarder defended his thesis on 13 June 2017. The title: Zebrafish as an IBD model.

Karen Ekkelund Petersen defended her thesis on 9 June 2017. The title:

Randi Lundberg defended her thesis on 8 May 2017 The title: Optimizing Microbiota Transplantation Studies in Mice - Effects of housing, diet, and donor on the microbiota and intestinal immunology”

David Højland Ipsen defended his thesis on 3 March 2017.The title: The guinea pig as a model for dyslipidemia and non-alcoholic fatty liver disease.

Kristine Rothaus Christensen defended her thesis on 28 February 2017. The title: Development and characterisation of haemophilic arthropathy in a rat model of haemophilia A.

PhD Defences 2016

Sarah Louise Tangsgaard Christensen has handed in her thesis for assessment. Work area: Development of a behavioural animal model of migraine.

Karin Maria Lövgren defended her thesis on 11 Nov. 2016. The title: Characterization of the immune response to coagulation factor VIII in a newly established haemophilia A rat.

Alessandro Virtuose defended his thesis on 14 Nov. 2016. The title: Decision makrin in rats - Evaluation of an optimal foraging-based paradigm and its applications to obesity research

Katja Maria Bendtsen defended her thesis on 28 June 2016. The title: Gut barrier, microbiota and immune environment in early life-influence on inflammatory disease models.

Daniel Vest Christophersen has handed in his thesis for assessment. Mechanisms of accelerated atherosclerosis by exposure to multi-walled carbon nanotubes

Bill Vestergaard defended his thesis on 18 March 2016. The title: Establishment and use of surgical rat models for assessment of organ specific in vivo clearance

PhD Defences 2015

Sara Marie Atkinson defended her thesis on 18 Dec. 2015 at 13.00. The Title: Pharmacological value of murine delayed-type hypersensitivity arthritis (DTHA) as a model for rheumatoid arthritis

Lisa Amanda Rottbøll defended her thesis on 2 Dec. 2015 at 13.00. The title:Microdialysis quantification of antimicrobials in the pig pulmonary epithelial lining fluid.

Vivi F.H. Jensen defended her thesis on 2 Oct. at 13.00. The title: Effects of persistent insulin-induced hypoglycaemia on the nervous system in non-diabetic Sprague-Dawley rats.

Merete Ellekilde defend her thesis on 30 June at 13.00. The title: Impact on the gut microbiota on glucose intolerance in mice.

Bettina Merete Pyndt defended her thesis on  24 April at 13.00.

Kristine Holgersen will defend her PhD thesis on 30 January at 13.00. The title: Piroxicam-accelerated colitis in interleukin-10 knockout mice; an in vivo model mimicking human inflammatory bowel disease

Britta Cathrina Poulsen will defend her PhD thesis on 20 January at 13.00. The title: Transfer of human atopic dermatitis skin-derived T cells into immunocompromised mice. 

PhD defences 2014

Ida Rune Sørensen will defend her PhD on 21 nov. at 13.00. The title: Development and Characterization of a Diabetic and Atherosclerotic Rodent Animal Model

Trine Pagh Ludvigsen defended her PhD on 22 october. The title: Development and characterization of a minipig of atherosclerosis - in vivo diagnosis and pathology.

Janne Gram Schjoldager defended her PhD on 31 January 2014. The title: Maternal vitamin C deficiency: Effects on pre-and postnatal development.

Britt Tranberg Christensen defended her PhD on 14 March 2014. The title: The impact of protein source and fat on metabolic risk factors in high-fat fed rats and mice.

Maya Devi Paidi defended her thesis on 28 March. The title: Molecular markers of pre-natal non-scorbutic vitamin C deficiency in foetal and young guinea pig brains

Mette Perch Groth defended her thesis on 4 April. The title: Animal Models of Haemophilia Complications

Anne Deen Christensen defended her thesis on 28 April The title: Applicability of a hapten-induced inflammation model for mechanistic in vivo studies.

Stine Hasselholt defended her thesis on 12 Sept. The title: Pre-and postnatal vitamin C deficiency in guinea pigs -distribution kinetics and redox modulation.

Katja C.M. Denninger defended her thesis on 10 June. The title "Chronic joint inflammation - Bone remodelling and the need for a systemic animal model of psoriatic arthritis”.

PhD defences 2013

Günaj Rakipovski defended his PhD in February 2013. The title: Exploration of glycemic fluctuations and oxidative stress in normal and insulin resistant rats.

Eva Bartholin Andreasen defended her PhD in March 2013. The title (in Danish), Hunden som spontan dyremodel til undersøgelser af sammenhængen mellem koagulation og cancer.

Anne Engedahl Pastoft defended her PhD in June 2013. The title: Establishment of a venous bleeding model in harmophillia A mice for evaluation of haemostatic effect of pro-coagulant compounds

Bettina Clausen: Development and characterization of a new and more predictive Alzheimer disease model

Eva Nygaard:Dietary fat, FGF21 and bodyweight homeostasis

Paulo Aranha defended his PhD in Nov. 2013. The title: Fate of Ptaquiloside in Dairy Cow

Zindy Raida defended her thesis 12 Dec. 2013. The title: Investigations in transgenic mouse models of permanent brain ischemia.

Kristina Bram Knudsen defended her thesis 13 Dec. 2013. The title: Toxicological assessment of nanoparticles intetnted as drug delivery carriers for the CNS.

PhD Defences 2012
Kirsten Rosenmaj Jacobsen defended her Phd in December 2012. The title: Refinement of non-invasive stress and pain assessment in laboratory mice - methodology and application.

Thomas Dahl Nissen defended his PhD in June 2012. The title: A novel nociceptive model of visceral rapid balloon distension: Electrophysiological evaluation and translational aspects.

Ditte Dencker Nielsen
defended her PhD in March 2012.
The title: Role of subpopulation of neuronal M4 muscarinic acetylcholine
receptors in regulation of dopaminergic neurotransmission.

Otto Kalliokoski defended his PhD in March 2012.
The title: Assessing laboratory rodent welfare through the use of stress sensitive biomarkers.