The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. 2023
  2. Published

    Dietary seaweed (Saccharina latissima) supplementation in pigs induces localized immunomodulatory effects and minor gut microbiota changes during intestinal helminth infection

    Bonde, C. S., Mejer, Helena, Myhill, Laura Jessica, Zhu, L., Jensen, Penille, Büdeyri Gökgöz, Nilay, Krych, Lukasz, Nielsen, Dennis Sandris, Skovgaard, K., Thamsborg, Stig Milan & Williams, Andrew Richard, 2023, In: Scientific Reports. 13, 16 p., 21931.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Dramatic increase in slaughter condemnations due to Escherichia coli ST23 and ST101 within the Danish broiler production

    Kromann, Sofie, Baig, S., Olsen, Rikke Heidemann, Edslev, S. M., Thoefner, Ida , Bojesen, Anders Miki, Jensen, Henrik Elvang & Stegger, M., 2023, In: Veterinary Microbiology. 280, 109696.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effects of Weaning Age and Creep Feed Type on Growth Performance and Gut Maturation in Weaned Piglets

    Lyderik, Kimmie Kyed, Zhang, X., Larsen, Christina, Kjeldsen, N. J., Pedersen, M. L. M., Hedemann, M. S., Williams, Andrew Richard, Williams, Charlotte Amdi & Madsen, Johannes Gulmann, 2023, In: Animals. 13, 11, 1851.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Effects of early postnatal gastric and colonic microbiota transplantation on piglet gut health

    Larsen, Christina, Offersen, Simone Margaard, Brunse, Anders, Pirolo, Mattia, Kar, S. K., Guadabassi, L. & Thymann, Thomas, 2023, In: Journal of Animal Science and Biotechnology. 14, 14 p., 158.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Establishment and application of an aerogenous model of avian colibacillosis

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Thoefner, Ida & Jensen, Henrik Elvang, 2023.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  7. Published

    Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice

    Rasmussen, Torben Sølbeck, Mentzel, Caroline M. Junker, Danielsen, M. R., Jakobsen, Rasmus Riemer, Zachariassen, L. S. F., Castro Mejia, J. L., Brunse, Anders, Hansen, Lars Hestbjerg, Hansen, Camilla Hartmann Friis, Hansen, Axel Kornerup & Nielsen, Dennis Sandris, 2023, In: Gut Microbes. 15, 1, 21 p., 2208504.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Fighting Irreproducibility in Preclinical Neuroscience Using a Meta-analytical Approach: The Case of the Chronic Unpredictable Stress Model of Depression

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hau, Jann, 2023, University of Copenhagen. 80 p.

    Research output: Book/Report › Ph.D. thesis › Research

  9. Published

    Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology

    Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Hair glucocorticoids are not a historical marker of stress: Exploring the time-scale of corticosterone incorporation into hairs in a rat model

    Colding-Jørgensen, Pernille, Hestehave, Sara, Abelson, Klas & Kalliokoski, Otto, 2023, In: General and Comparative Endocrinology. 341, 11 p., 114335.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Increased meal-induced neurotensin response predicts successful maintenance of weight loss: Data from a randomized controlled trial

    Brethvad, Annemette Overgaard, Zakariassen, Hannah Louise, Holt, Joachim, Lundgren, J. R., Jakobsen, A., Hartmann, Bolette, Lehmann, E. W., Kissow, Hannelouise, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Holst, Birgitte, 2023, In: Metabolism: Clinical and Experimental. 143, 8 p., 155534.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Influence of general anaesthesia on circulating biomarkers of glucose metabolism in pigs

    Christoffersen, B. Ø., Bundgaard, C. J., Hjøllund, K. R., Fels, J. J., Boll, K. K., Lyhne, Mille Kronborg & Olsen, Lisbeth Høier, 2023, In: Laboratory Animals. 57, 6, p. 650-663

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs

    Christiansen, Line Iadsatian, Holmqvist, B., Pan, X., Holgersen, Kristine, Lindholm, S. E. H., Henriksen, Nicole Lind, Burrin, D. G., Ley, D., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: eNeuro. 10, 4, ENEURO.0430-22.2023.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs

    Christiansen, Line Iadsatian, Ventura, G. C., Holmqvist, B., Aasmul-Olsen, Karoline, Lindholm, S. E. H., Lycas, M. D., Mori, Yuki, Secher, Jan Bojsen-Møller, Burrin, D. G., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: Frontiers in Neuroscience. 17, 15 p., 1205819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Intrauterine growth restriction in piglets modulates postnatal immune function and hepatic transcriptional responses independently of energy intake

    Williams, Charlotte Amdi, Larsen, Christina, Jensen, K. M. R., Tange, E. Ø., Sato, Helena & Williams, Andrew Richard, 2023, In: Frontiers in Physiology. 14, 10 p., 1254958.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

    Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Neonatal prophylactic antibiotics after preterm birth affect plasma proteome and immune development in pigs

    Muk (Mudi), Tik, Leto, A., Brunse, Anders, Stensballe, A., Thymann, Thomas, Sangild, Per Torp & Nguyen, Duc Ninh, 2023, In: Pediatric Research. 94, p. 530–538

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response

    Reimann, Maria Josefine, Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, Signe Emilie, Møller, J. E., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Internal Medicine. 37, 6, p. 1947-2660

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs

    Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33 1 p., O11.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  20. Published

    Pharmacological safety of dimethoxy curcumin-human serum albumin conjugate for potential therapeutic purpose

    Korah, M. C., Sreelatha, Harikrishnan Vijayakumar, Deepa, S., Arya, A., Sabareeswaran, A., Mohanan, P. V. & Krishnan, L. K., 2023, In: Canadian Journal of Physiology and Pharmacology. 101, 6, p. 304-315

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Rethinking data treatment: The sucrose preference threshold for anhedonia in stress-induced rat models of depression

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2023, In: Journal of Neuroscience Methods. 395, 11 p., 109910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

    Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Transplantation of fecal filtrate to neonatal pigs reduces post-weaning diarrhea: A pilot study

    Larsen, Christina, Andersen, A. B., Sato, Helena, Brunse, Anders & Thymann, Thomas, 2023, In: Frontiers in Veterinary Science. 10, 12 p., 1110128.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Ultra-High Temperature Treatment of Liquid Infant Formula, Systemic Immunity, and Kidney Development in Preterm Neonates

    Sun, Jing, Akıllıoğlu, H. G., Zhong, Jingren, Muk (Mudi), Tik, Pan, X., Lund, Marianne N., Sangild, Per Torp, Nguyen, Duc Ninh & Bering, S. B., 2023, In: Molecular Nutrition and Food Research. 67, 24, 12 p., 2300318.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2024
  26. Published

    A Gently Processed Skim Milk-Derived Whey Protein Concentrate for Infant Formula: Effects on Gut Development and Immunity in Preterm Pigs

    Aasmul-Olsen, Karoline, Akıllıoğlu, H. G., Christiansen, Line Iadsatian, Engholm-Keller, Kasper, Brunse, Anders, Stefanova, Denitsa Vladimirova, Bjørnshave, A., Bechshøft, M. R., Skovgaard, K., Thymann, Thomas, Sangild, Per Torp, Lund, Marianne N. & Bering, S. B., 2024, In: Molecular Nutrition and Food Research. 68, 6, 2300458.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction

    Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  28. Published

    Diet composition drives tissue-specific intensity of murine enteric infections

    Israelson, H., Vedsted-Jakobsen, Amalie, Zhu, L., Gagnaire, A., von Münchow, Alexandra, Polakovicova, N., Valente, Angela Hørdum, Raza, Ali, Andersen-Civil, A. I. S., Olsen, John Elmerdahl, Myhill, Laura Jessica, Geldhof, P. & Williams, Andrew Richard, 2024, In: mBio. 15, 2, 22 p., e0260323.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Effects of inhibition of Nav1.3, Nav1.7, and Nav1.8 channels on pain-related behavior in Speke's hinge-back tortoise (Kinixys spekii)

    Musembi Makau, Christopher, Towett, P. K., Kanui, T. I. & Abelson, Klas, 2024, In: Journal of Neuroscience Research. 102, 1, e25274.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Finding new analgesics: Computational pharmacology faces drug discovery challenges

    Barakat, Ahmed, Munro, G. & Heegaard, Anne-Marie, 2024, In: Biochemical Pharmacology. 222, 21 p., 116091.

    Research output: Contribution to journal › Review › Research › peer-review

  31. E-pub ahead of print

    Glucose-regulatory hormones and growth in very preterm infants fed fortified human milk

    Holgersen, Kristine, Rasmussen, Martin Bo, Zamir, I., Aunsholt, Lise, Zachariassen, G. & Sangild, Per Torp, 2024, (E-pub ahead of print) In: Pediatric Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. E-pub ahead of print

    Gut development following insulin-like growth factor-1 supplementation to preterm pigs

    Rasmussen, Martin Bo, Holgersen, Kristine, Pankratova, Stanislava, Bæk, Ole, Burrin, D. G., Thymann, Thomas & Sangild, Per Torp, 2024, (E-pub ahead of print) In: Pediatric Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Insulin-like growth factor 1 associated with altered immune responses in preterm infants and pigs

    Bæk, Ole, Rasmussen, Martin Bo, Gerts, T., Aunsholt, Lise, Zachariassen, G., Sangild, Per Torp & Nguyen, Duc Ninh, 2024, In: Pediatric Research. 95, p. 120–128 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Refinement of the motorised laminectomy-assisted rat spinal cord injury model by analgesic treatment

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2024, In: PLoS ONE. 19, 1 , 23 p., e0294720.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Reliability of sucrose preference testing following short or no food and water deprivation—a Systematic Review and Meta-Analysis of rat models of chronic unpredictable stress

    Berrio Sanchez, Jenny Paola, Hestehave, Sara & Kalliokoski, Otto, 2024, In: Translational Psychiatry. 14, 1, 10 p., 39.

    Research output: Contribution to journal › Review › Research › peer-review

  36. E-pub ahead of print

    Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

    Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.

    Research output: Contribution to journal › Journal article › Research › peer-review

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