The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. Published

    [68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction

    Bentsen, Simon, Clemmensen, Andreas Høeg, Loft, Mathias Hougaard, Flethøj, M., Debes, Karina Poulsdóttir, Ludvigsen, Trine Pagh, Larsen, C. B., Kirchhoff, J., Olsen, Lisbeth Høier, Møller, J. E., Andersen, Thomas Lund, Johannesen, Helle Hjorth, Jespersen, Thomas & Kjær, Andreas, 2021, In: Diagnostics. 11, 10, 1807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    We need to talk about fraudulent animal studies: learnings from a systematic review

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2022, In: Laboratory Animals. 56, S1, p. 172-172 PD15.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig

    Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

    Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide

    Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Vascular and lung function related to ultrafine and fine particles exposure assessed by personal and indoor monitoring: a cross-sectional study

    Olsen, Y., Karottki, D. G., Jensen, Ditte Marie, Bekö, G., Kjeldsen, B. U., Clausen, G., Hersoug, L., Holst, G. J., Wierzbicka, A., Sigsgaard, T., Linneberg, Allan René, Møller, Peter & Loft, Steffen, 2014, In: Environmental Health. 13, p. 1-10 10 p., 112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models

    Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. E-pub ahead of print

    Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

    Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Ultra-High Temperature Treatment of Liquid Infant Formula, Systemic Immunity, and Kidney Development in Preterm Neonates

    Sun, Jing, Akıllıoğlu, H. G., Zhong, Jingren, Muk (Mudi), Tik, Pan, X., Lund, Marianne N., Sangild, Per Torp, Nguyen, Duc Ninh & Bering, S. B., 2023, In: Molecular Nutrition and Food Research. 67, 24, 12 p., 2300318.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Ultra-High Temperature Treatment and Storage of Infant Formula Induces Dietary Protein Modifications, Gut Dysfunction, and Inflammation in Preterm Pigs

    Sun, Jing, Akıllıoğlu, H. G., Aasmul-Olsen, Karoline, Ye, Y., Lund, P., Zhao, X., Brunse, Anders, Nielsen, C. F., Chatterton, Dereck Edward Winston, Sangild, Per Torp, Lund, Marianne N. & Bering, S. B., 2022, In: Molecular Nutrition & Food Research. 66, 20, 13 p., 2200132.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Transplantation of fecal filtrate to neonatal pigs reduces post-weaning diarrhea: A pilot study

    Larsen, Christina, Andersen, A. B., Sato, Helena, Brunse, Anders & Thymann, Thomas, 2023, In: Frontiers in Veterinary Science. 10, 12 p., 1110128.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Training improves oxidative capacity, but not function, in spinal muscular atrophy type III

    Madsen, K. L., Wils, Regitze Sølling, Preisler, N., Thøgersen, F., Berthelsen, M. P. & Vissing, John, Aug 2015, In: Muscle & Nerve. 52, 2, p. 240–244 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The selective 5-HT2A receptor agonist 25CN-NBOH does not affect reversal learning in mice

    Odland, Anna Ulstein, Kristensen, Jesper Langgaard & Andreasen T., Jesper, 2021, In: Behavioural Pharmacology. 32, 5, p. 448-452

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

    Jensen, Anders A., Halberstadt, A. L., Marcher, Emil, Odland, Anna Ulstein, Chatha, M., Speth, N., Liebscher, G., Hansen, M., Bräuner, Hans, Palner, M., Andreasen T., Jesper & Kristensen, Jesper Langgaard, 2020, In: Biochemical Pharmacology. 177, 16 p., 113979.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

    Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The effect of feeding liquid or dry creep feed on growth performance, feed disappearance, enzyme activity and number of eaters in suckling piglets

    Byrgesen, N., Madsen, Johannes Gulmann, Larsen, Christina, Kjeldsen, N. J., Cilieborg, Malene Skovsted & Williams, Charlotte Amdi, 2021, In: Animals. 11, 11, 3144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis

    Ipsen, David Højland, Skat-Rørdam, Josephine, Svenningsen, M., Andersen, Mia Trein, Latta, M., Buelund, Lene Elisabeth, Lintrup, K., Skaarup, R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 4, p. 583-593

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs

    Ipsen, David Højland, Agerskov, R. H., Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Scientific Reports. 11, 2955.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The counterregulatory response to hypoglycaemia in the pig

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Ludvigsen, T. P., Porsgaard, T., Schou-Pedersen, A. M. V., Fels, J. J., Lykkesfeldt, Jens & Refsgaard, H. H. F., Oct 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 278-286

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The adjuvant-induced rat model of monoarthritis: welfare implications and possible refinement strategies

    Berke, M. S. & Abelson, Klas, 2020, In: Scandinavian Journal of Laboratory Animal Science. 46, 5, p. 39-50 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Temporal development of dyslipidemia and nonalcoholic fatty liver disease (Nafld) in syrian hamsters fed a high‐fat, high‐fructose, high‐cholesterol diet

    Jensen, Victoria Svop, Fledelius, C., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Nutrients. 13, 2, p. 1-18 18 p., 604.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Telomere length and genotoxicity in the lung of rats following intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Løhr, M., Sheykhzade, Majid, Lykkesfeldt, Jens, Wils, Regitze Sølling, Loft, Steffen & Møller, Peter, 2019, In: Mutagenesis. 34, 2, p. 203-214 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Telomere dynamics and cellular senescence: an emerging field in environmental and occupational toxicology

    Møller, Peter, Wils, Regitze Sølling, Jensen, Ditte Marie, Andersen, M. H. G. & Roursgaard, Martin, 2018, In: Critical Reviews in Toxicology. 48, 9, p. 761-788 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice

    Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Systematic review of 316 animal models of bone infections - a call for improved quality

    Jensen, Louise Kruse, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie & Jensen, Henrik Elvang, 21 Mar 2019.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  29. Published

    Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain

    Zhang, X. Y., Barakat, Ahmed, Diaz-delCastillo, M., Vollert, J., Sena, E. S., Heegaard, Anne-Marie, Rice, A. S. C. & Soliman, N., 2022, In: Pain. 163, 11, p. 2076-2102

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Suckling Induces Differential Gut Enzyme Activity and Body Composition Compared to Feeding Milk Replacer in Piglets

    Williams, Charlotte Amdi, Pedersen, M. L. M., Larsen, Christina, Klaaborg, J., Williams, Andrew Richard & Madsen, Johannes Gulmann, 2022, In: Animals. 12, 22, 3112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Brockhoff, P. M. B., Seested, T. & Refsgaard, H. H. F., 2020, In: Experimental and Clinical Endocrinology and Diabetes. 128, 5, p. 332-338 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Stability and development of psychotic symptoms and the use of antipsychotic medication - long-term follow-up

    Gotfredsen, D. R., Wils, Regitze Sølling, Hjorthøj, C., Austin, Stephen Fitzgerald, Albert, N., Secher, R. G., Thorup, Anne, Mors, O. & Nordentoft, Merete, Sep 2017, In: Psychological Medicine. 47, 12, p. 2118-2129 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing

    Lützhøft, Ditte Olsen, Sánchez-Alcoholado, L., Tougaard, P., Mentzel, Caroline M. Junker, Kot, Witold, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 126, p. 227-232 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Sex-Specific Survival, Growth, Immunity and Organ Development in Preterm Pigs as Models for Immature Newborns

    Bæk, Ole, Cilieborg, Malene Skovsted, Nguyen, Duc Ninh, Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 12 p., 626101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation

    Jensen, Ditte Marie, Skovsted, Gry Freja, Bonde, M. F. B., Bentzon, J. F., Rolin, B., Franck, G., Ougaard, M. K. E., Voetmann, Louise Marie, Bachmann, J. C., Uryga, A., Pyke, C., Kirk, R. K., Hvid, H., Knudsen, L. B., Lykkesfeldt, Jens & Nyberg, M., 2022, In: Atherosclerosis Plus. 49, p. 32-41 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Searching for assay controls for the Fpg- and hOGG1-modified comet assay

    Møller, Peter, Jantzen, K., Løhr, M., Andersen, M. H., Jensen, Ditte Marie, Roursgaard, Martin, Danielsen, P. H., Jensen, Annie & Loft, Steffen, 24 Feb 2018, In: Mutagenesis. 33, 1, p. 9-19 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

    Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Role of oxidative stress in carbon nanotube-generated health effects

    Møller, P., Christophersen, D. V., Jensen, Ditte Marie, Kermanizadeh, A., Roursgaard, Martin, Jacobsen, N. R., Hemmingsen, J. G., Danielsen, P. H., Cao, Y., Jantzen, K., Klingberg, H., Hersoug, L. & Loft, Steffen, Nov 2014, In: Archives of Toxicology. 88, 11, p. 1939-64 26 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research

    Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)

    Brandt, S. D., Kavanagh, P. V., Westphal, F., Stratford, A., Odland, Anna Ulstein, Klein, A. K., Dowling, G., Dempster, N. M., Wallach, J., Passie, T. & Halberstadt, A. L., 2020, In: Drug Testing and Analysis. 12, p. 812-826

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Rethinking data treatment: The sucrose preference threshold for anhedonia in stress-induced rat models of depression

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2023, In: Journal of Neuroscience Methods. 395, 11 p., 109910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Reliability of sucrose preference testing following short or no food and water deprivation—a Systematic Review and Meta-Analysis of rat models of chronic unpredictable stress

    Berrio Sanchez, Jenny Paola, Hestehave, Sara & Kalliokoski, Otto, 2024, In: Translational Psychiatry. 14, 1, 10 p., 39.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Refinement of the spinal cord injury rat model and validation of its applicability as a model for memory loss and chronic pain

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2021, In: Heliyon. 7, 7, 11 p., e07500.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Refinement of the rat contusion model of thoracic spinal cord injury

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 27-27 S2B3.1.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  45. Published

    Refinement of the motorised laminectomy-assisted rat spinal cord injury model by analgesic treatment

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2024, In: PLoS ONE. 19, 1 , 23 p., e0294720.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Reduced early life mucosal integrity decreases thymic cell counts and increases local, but not thymic regulatory, T cell recruitment: Gut mucosal integrity breach and thymic T cells

    Zakariassen, Hannah Louise, Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2019, In: European Journal of Inflammation. 17, p. 1-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Receptor Activator of Nuclear Factor kappa-B Ligand is Not Regulated During Chronic Osteomyelitis in Pigs

    Lüthje, F. L., Skovgaard, K., Jensen, Henrik Elvang, Blirup-Plum, Sophie Amalie, Henriksen, Nicole Lind, Aalbæk, Bent & Jensen, Louise Kruse, 2020, In: Journal of Comparative Pathology. 179, p. 7-24 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Rapid Postnatal Adaptation of Neurodevelopment in Pigs Born Late Preterm

    Nielsen, Charlotte Holme, Bladt Brandt, A., Thymann, Thomas, Obelitz-Ryom, K., Jiang, Pingping, Vanden Hole, C., van Ginneken, C., Pankratova, Stanislava & Sangild, Per Torp, 2019, In: Developmental Neuroscience. 40, 5-6, 15 p., 586–600.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Randall Selitto pressure algometry for assessment of bone-related pain in rats

    Falk, S., Ipsen, David Højland, Appel, C. K., Ugarak, A., Durup, D., Dickenson, A. H. & Heegaard, Anne-Marie, 2015, In: European Journal of Pain. 19, 3, p. 305-312 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013.

    Research output: Contribution to conference › Poster › Research

  51. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Protective potential of an autogenous vaccine in an aerogenous model of escherichia coli infection in broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Vaccines. 9, 11, 1233.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Prenatal Intra-Amniotic Endotoxin Induces Fetal Gut and Lung Immune Responses and Postnatal Systemic Inflammation in Preterm Pigs

    Nguyen, Duc Ninh, Thymann, Thomas, Goericke-Pesch, S. K., Ren, S., Wei, W., Skovgaard, K., Damborg, Peter Panduro, Brunse, Anders, van Gorp, C., Kramer, B. W., Wolfs, T. G. & Sangild, Per Torp, 2018, In: American Journal of Pathology. 188, 11, p. 2629-2643 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Polymorphisms in the serotonin transporter gene do not associate with myxomatous mitral valve disease or circulating serotonin levels in Cavalier King Charles Spaniels

    Reimann, Maria Josefine, 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  55. Published

    Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Plasma and serum serotonin concentrations and surface-bound platelet serotonin expression in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2015, In: American Journal of Veterinary Research. 76, 6, p. 520-531 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Pharmacological safety of dimethoxy curcumin-human serum albumin conjugate for potential therapeutic purpose

    Korah, M. C., Sreelatha, Harikrishnan Vijayakumar, Deepa, S., Arya, A., Sabareeswaran, A., Mohanan, P. V. & Krishnan, L. K., 2023, In: Canadian Journal of Physiology and Pharmacology. 101, 6, p. 304-315

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Perioperative nivolumab monotherapy versus nivolumab plus ipilimumab in resectable hepatocellular carcinoma: a randomised, open-label, phase 2 trial

    Kaseb, A. O., Hasanov, E., Cao, H. S. T., Xiao, L., Vauthey, J. N., Lee, S. S., Yavuz, B. G., Mohamed, Y. I., Qayyum, A., Jindal, S., Duan, F., Basu, S., Yadav, S. S., Nicholas, C., Sun, J. J., Singh Raghav, K. P., Rashid, A., Carter, K., Chun, Y. S., Tzeng, C. W. D. & 9 others, Sakamuri, D., Xu, L., Sun, R., Cristini, V., Beretta, L., Yao, J. C., Wolff, R. A., Allison, J. P. & Sharma, P., 2022, In: The Lancet Gastroenterology and Hepatology. 7, 3, p. 208-218 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs

    Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, S. B. & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Parasites and plants - bioactive compounds with anti-parasitic effect from Cichorium intybus

    Valente, Angela Hørdum, de Roode, B. M., Williams, Andrew Richard, Simonsen, H. T. & Thamsborg, Stig Milan, 2019, In: Planta Medica. 85, 18, p. 1420-1420

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  61. Published

    Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

    Møller, Peter, Danielsen, P. H., Karottki, D. G., Jantzen, K., Roursgaard, Martin, Klingberg, H., Jensen, Ditte Marie, Christophersen, D. V., Hemmingsen, J. G., Cao, Y. & Loft, Steffen, 2014, In: Mutation Research - Reviews. 762, p. 133-166 34 p.

    Research output: Contribution to journal › Review › Research › peer-review

  62. Published

    Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs

    di Ianni, Emilio, Møller, Peter, Mortensen, A., Szarek, J., Clausen, P. A., Saber, A. T., Vogel, U. & Jacobsen, N. R., 2020, In: Nanotoxicology. 14, 7, p. 869-892 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir

    Pedersen, K., Gradel, Anna Katrina Jógvansdóttir, Ludvigsen, T. P., Christoffersen, B. Ø., Fuglsang-Damgaard, C. A., Bendtsen, K. M., Madsen, S. H., Manfé, V. & Refsgaard, H. H. F., 2022, In: Translational Research. 239, p. 71-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Optimising the sampling procedure for forensic investigation of bruises on pigs

    Barington, Kristiane, Skovgaard, K., Henriksen, Nicole Lind & Jensen, Henrik Elvang, 2020, In: Veterinary Record. 187, 4, 153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs

    Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33 1 p., O11.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  66. Published

    Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs

    Ahnfeldt, Agnethe May, Bæk, Ole, Hui, Y., Nielsen, Charlotte Holme, Obelitz-Ryom, K., Busk-Anderson, T., Ruge, A., Holst, Jens Juul, Rudloff, S., Burrin, D., Nguyen, Duc Ninh, Nielsen, Dennis Sandris, Zachariassen, G., Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2020, In: The Journal of Nutrition. 150, 5, p. 1196-1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Nutrient Fortification of Human Donor Milk Affects Intestinal Function and Protein Metabolism in Preterm Pigs

    Sun, Jing, Li, Y., Nguyen, Duc Ninh, Mortensen, M. S., van den Akker, C. H. P., Skeath, T., Pors, S. E., Pankratova, Stanislava, Rudloff, S., Sørensen, Søren Johannes, Burrin, D. G., Thymann, Thomas & Sangild, Per Torp, 2018, In: Journal of Nutrition. 148, 3, p. 336-347 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs

    Frederiksen, Henriette Reventlow S, Skov, Søren, Tveden-Nyborg, Pernille, Freude, Kristine & Doehn, U., 7 May 2024, In: Stem Cell Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Normal Weight Dyslipidemia: Is It All About the Liver?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  70. Published

    Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

    Frederiksen, Henriette Reventlow S, Doehn, U., Tveden-Nyborg, Pernille & Freude, Kristine, 2021, In: Frontiers in Genome Editing. 2, 623717.

    Research output: Contribution to journal › Review › Research › peer-review

  71. Published

    No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response

    Reimann, Maria Josefine, Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, Signe Emilie, Møller, J. E., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Internal Medicine. 37, 6, p. 1947-2660

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Neonatal prophylactic antibiotics after preterm birth affect plasma proteome and immune development in pigs

    Muk (Mudi), Tik, Leto, A., Brunse, Anders, Stensballe, A., Thymann, Thomas, Sangild, Per Torp & Nguyen, Duc Ninh, 2023, In: Pediatric Research. 94, p. 530–538

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Necrotizing enterocolitis is associated with acute brain responses in preterm pigs

    Sun, Jing, Pan, X., Christiansen, Line Iadsatian, Yuan, X., Skovgaard, K., Chatterton, Dereck Edward Winston, Kaalund, S. S., Gao, Fei, Sangild, Per Torp & Pankratova, Stanislava, 2018, In: Journal of Neuroinflammation. 15, 13 p., 180.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

    Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Myxømatøs mitralklapsygdom hos hund: Metoder til diagnostik af behandlingskrævende sygdomsstadier

    Reimann, Maria Josefine, Christiansen, L. B., Falk, T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 9, p. 28-32

    Research output: Contribution to journal › Review › Research › peer-review

  76. Published

    My journey towards higher education in laboratory animal science - a big thanks to European teaching and Laboratory Animals Limited (LAL) funding!

    Sreelatha, Harikrishnan Vijayakumar, 2022, In: Laboratory Animals. 56, 5, p. 491-492

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  77. Published

    Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  78. Published

    Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model

    Ipsen, David Højland, Skat-Rørdam, Josephine, Tsamouri, M. M., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Molecular Genetics and Genomics. 294, 3, p. 649–661

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Modulation of nociception by tricyclic antidepressants in the Speke’s hinge-back tortoise

    Musembi Makau, Christopher, 2022, Canadian Society for Brain, Behaviour, and Cognitive Science: CBBCS 2022 - 32nd Annual Meeting in Halifax, Nova Scotia. Halifax, Canada, p. 44-44

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review

  80. Published

    Modulation of nociception by noradrenaline and serotonin receptor systems in speke’s hinge-back tortoise

    Musembi Makau, Christopher & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 128-129 PA15.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  81. Published

    Modulation of nociception by amitriptyline hydrochloride in the Speke’s hinge-back tortoise (Kiniskys spekii)

    Musembi Makau, Christopher, Towett, P. K., Abelson, Klas & Kanui, T. I., 2021, In: Veterinary Medicine and Science. 7, 3, p. 1034-1041

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Modelling nonalcoholic steatohepatitis in vivo—a close transcriptomic similarity supports the guinea pig disease model

    Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Sep 2021, In: Biomedicines. 9, 9, 1198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

    Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels

    Reimann, Maria Josefine, Moller, J. E., Haggstrom, J., Martinussen, Torben, Zatrazemi, S. S. C., Svanholm, L., Nielsen, L. B. M., Pedersen, H. D. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 4, p. 1008-1016 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Milk osteopontin for gut, immunity and brain development in preterm pigs

    Aasmul-Olsen, Karoline, Henriksen, Nicole Lind, Nguyen, Duc Ninh, Heckmann, A. B., Thymann, Thomas, Sangild, Per Torp & Bering, S. B., 2021, In: Nutrients. 13, 8, 2675.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals

    Møller, Peter, Jensen, Ditte Marie, Christophersen, D. V., Kermanizadeh, A., Jacobsen, N. R., Hemmingsen, J. G., Danielsen, P. H., Karottki, D. G., Roursgaard, Martin, Cao, Y., Jantzen, K., Klingberg, H., Hersoug, L. & Loft, Steffen, Mar 2015, In: Environmental and Molecular Mutagenesis. 56, 2, p. 97-110 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  87. Published

    Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration

    Reimann, Maria Josefine, Haggstrom, J., Moller, J. E., Lykkesfeldt, Jens, Falk, T. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets

    Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Longitudinal study on background lesions in broiler breeder flocks and their progeny, and genomic characterisation of Escherichia coli

    Kromann, Sofie, Baig, S., Stegger, M., Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2022, In: Veterinary Research. 53, 52.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Long-term excess fat and/or fructose ingestion causes changes in small artery K+ transporter expression and function with effects on blood pressure

    Gradel, Anna Katrina Jógvansdóttir, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik & Jensen, Lars Jørn, 22 Sep 2016. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  92. Published

    Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SKCa, IKCa, and Kir2.1 channels

    Gradel, Anna Katrina Jógvansdóttir, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik & Jensen, Lars Jørn, 28 Feb 2018, In: Clinical Science. 132, 4, p. 461–474 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Long term Westernized diet leads to region-specific changes in brain signaling mechanisms

    Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

    Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis

    Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Late-onset Pompe disease is prevalent in unclassified limb-girdle muscular dystrophies

    Preisler, N., Lukacs, Z., Vinge, L., Madsen, K. L., Husu, E., Wils, Regitze Sølling, Duno, M., Andersen, H., Laub, M. S. H. & Vissing, John, 2013, In: Molecular Genetics and Metabolism. 110, 3, p. 287-289 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Is sweet consumption under thirst and hunger really a good indicatior or depression?

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hestehave, S., 2022, In: Laboratory Animals. 56, S1, p. 25-26 S2A5.4.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  98. Published

    Investigation of noradrenergic receptor system in anti-nociception using formalin test in the naked mole rat (Heterocephalus glaber)

    Mwobobia, Royford, Kanui, T. I. & Abelson, Klas, Oct 2020, In: Heliyon. 6, 10, 6 p., e05216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Intrauterine growth restriction in piglets modulates postnatal immune function and hepatic transcriptional responses independently of energy intake

    Williams, Charlotte Amdi, Larsen, Christina, Jensen, K. M. R., Tange, E. Ø., Sato, Helena & Williams, Andrew Richard, 2023, In: Frontiers in Physiology. 14, 10 p., 1254958.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs

    Christiansen, Line Iadsatian, Ventura, G. C., Holmqvist, B., Aasmul-Olsen, Karoline, Lindholm, S. E. H., Lycas, M. D., Mori, Yuki, Secher, Jan Bojsen-Møller, Burrin, D. G., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: Frontiers in Neuroscience. 17, 15 p., 1205819.

    Research output: Contribution to journal › Journal article › Research › peer-review

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