The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. Published

    Glucose supply and glycolysis inhibition shape the clinical fate of Staphylococcus epidermidis-infected preterm newborns

    Muk (Mudi), Tik, Brunse, Anders, Henriksen, Nicole Lind, Aasmul-Olsen, Karoline & Nguyen, Duc Ninh, 2022, In: JCI Insight. 7, 11, 18 p., e157234.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. E-pub ahead of print

    Glucose-regulatory hormones and growth in very preterm infants fed fortified human milk

    Holgersen, Kristine, Rasmussen, Martin Bo, Zamir, I., Aunsholt, Lise, Zachariassen, G. & Sangild, Per Torp, 2024, (E-pub ahead of print) In: Pediatric Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Growth Restriction and Systemic Immune Development in Preterm Piglets

    Bæk, Ole, Sangild, Per Torp, Thymann, Thomas & Nguyen, Duc Ninh, 2019, In: Frontiers in Immunology. 10, 2402.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Guideline for Preclinical Studies of Bone Infections in Large Animals Based on a Systematic Review of 316 Non-Rodent Models

    Jensen, Louise Kruse, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie & Jensen, Henrik Elvang, 2019, In: The Journal of bone and joint surgery. American volume. 101, 21, p. 1894-1903 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Guideline for preclinical studies of bone infections

    Jensen, Louise Kruse, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie & Jensen, Henrik Elvang, 12 Sep 2019.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  6. Published

    Guidelines for porcine models of human bacterial infections

    Jensen, Louise Kruse, Henriksen, Nicole Lind & Jensen, Henrik Elvang, 2019, In: Laboratory Animals. 53, 2, p. 125-136

    Research output: Contribution to journal › Review › Research › peer-review

  7. E-pub ahead of print

    Gut development following insulin-like growth factor-1 supplementation to preterm pigs

    Rasmussen, Martin Bo, Holgersen, Kristine, Pankratova, Stanislava, Bæk, Ole, Burrin, D. G., Thymann, Thomas & Sangild, Per Torp, 2024, (E-pub ahead of print) In: Pediatric Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Hair glucocorticoids are not a historical marker of stress: Exploring the time-scale of corticosterone incorporation into hairs in a rat model

    Colding-Jørgensen, Pernille, Hestehave, Sara, Abelson, Klas & Kalliokoski, Otto, 2023, In: General and Comparative Endocrinology. 341, 11 p., 114335.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Hair glucocorticoids are not a historical marker of stress: exploring the time-scale of corticosterone incorporation into hairs in a rat model

    Colding-Jørgensen, Pernille, Hestehave, Sara, Abelson, Klas & Kalliokoski, O., 2020, bioRxiv, 21 p.

    Research output: Working paper › Preprint › Research

  10. Published

    Health effects of exposure to diesel exhaust in diesel-powered trains

    Andersen, M. H. G., Frederiksen, M., Saber, A. T., Wils, Regitze Sølling, Fonseca, A. S., Koponen, I. K., Johannesson, S., Roursgaard, Martin, Loft, Steffen, Møller, Peter & Vogel, U., 2019, In: Particle and Fibre Toxicology. 16, 14 p., 21.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Hemostatic parameters in preterm and full-term pigs of identical postnatal age

    Krogh, Anne Kirstine Havnsøe, Brunse, Anders, Thymann, Thomas, Bochsen, L. & Kristensen, Annemarie T., 20 Oct 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  12. Published

    Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis—Roles as Putative Treatment Targets?

    Zisser, Alexandra, Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 4, 365.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    High Parenteral Support Volume Is Associated With Reduced Quality of Life Determined by the Short‐Bowel Syndrome Quality of Life Scale in Nonmalignant Intestinal Failure Patients

    Nordsten, C. B., Mølsted, Stig, Bangsgaard, L., Fuglsang, K. A., Brandt, C. F., Niemann, Mads Jacob & Jeppesen, Palle Bekker, 1 Jul 2021, In: Journal of Parenteral and Enteral Nutrition. 45, 5, p. 926-932 7 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  14. Published

    High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs

    Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    High-level serotonin binding in subpopulation of highly activated platelets in cavalier King charles spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  16. Published

    Housing behaviour of the naked mole rat (Heterocephalus glaber) under laboratory conditions

    Mwobobia, Royford, Abelson, Klas & Kanui, T. I., 2020, In: Scandinavian Journal of Laboratory Animal Science. 46, 1, p. 16-24 9 p., 2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Human Milk Fortification with Bovine Colostrum Is Superior to Formula-Based Fortifiers to Prevent Gut Dysfunction, Necrotizing Enterocolitis, and Systemic Infection in Preterm Pigs

    Sun, Jing, Li, Y., Pan, X., Nguyen, Duc Ninh, Brunse, Anders, Bojesen, Anders Miki, Rudloff, S., Mortensen, M. S., Burrin, D. G. & Sangild, Per Torp, 2019, In: Journal of Parenteral and Enteral Nutrition. 43, 2, p. 252-262

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Hyperinsulinaemic hypoglycaemia in non-anaesthetized Göttingen minipigs induces a counter-regulatory endocrine response and electrocardiographic changes

    Lyhne, Mille Kronborg, Vegge, A., Povlsen, G. K., Slaaby, R., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2021, In: Scientific Reports. 11, 11 p., 5983.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Identification of compounds responsible for the anthelmintic effects of chicory (Cichorium intybus) by molecular networking and bio-guided fractionation

    Valente, Angela Hørdum, de Roode, M., Ernst, M., Peña-Espinoza, M., Bornancin, L., Bonde, C. S., Martínez-Valladares, M., Ramünke, S., Krücken, J., Simonsen, H. T., Thamsborg, Stig Milan & Williams, Andrew Richard, 2021, In: International Journal for Parasitology: Drugs and Drug Resistance. 15, p. 105-114 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Imiquimod does not elicit inflammatory responses in the skin of the naked mole rat (Heterocephalus glaber)

    Kisipan, Mosiany Letura, Ojoo, R. O., Kanui, T. I. & Abelson, Klas, 5 Sep 2020, In: BMC Research Notes. 13, 6 p., 416.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Impaired Neonatal Immunity and Infection Resistance Following Fetal Growth Restriction in Preterm Pigs

    Bæk, Ole, Ren, S., Brunse, Anders, Sangild, Per Torp & Nguyen, Duc Ninh, 2020, In: Frontiers in Immunology. 11, 1808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function

    Voetmann, Louise Marie, Underwood, C. R., Rolin, B., Hansen, Axel Kornerup, Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    In vitro synergy of sertraline and tetracycline cannot be reproduced in pigs orally challenged with a tetracycline resistant Escherichia coli

    Kromann, Sofie, Hvidtfeldt, A., Boye, M., Sørensen, Dorte Bratbo, Jørgensen, S., Nielsen, Jens Peter & Olsen, Rikke Heidemann, 2019, In: BMC Microbiology. 19, 1, 12 p., 12.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants

    Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Increased meal-induced neurotensin response predicts successful maintenance of weight loss: Data from a randomized controlled trial

    Brethvad, Annemette Overgaard, Zakariassen, Hannah Louise, Holt, Joachim, Lundgren, J. R., Jakobsen, A., Hartmann, Bolette, Lehmann, E. W., Kissow, Hannelouise, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Holst, Birgitte, 2023, In: Metabolism: Clinical and Experimental. 143, 8 p., 155534.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease

    Reimann, Maria Josefine, Ljungvall, I., Hillstrom, A., Møller, J. E., Hagman, R., Falk, T., Hoglund, K., Haggstrom, J. & Olsen, Lisbeth Høier, Mar 2016, In: Veterinary Journal. 209, p. 113-118

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Infant Formula Based on Milk Fat Affects Immune Development in Both Normal Birthweight and Fetal Growth Restricted Neonatal Piglets

    Bæk, Ole, Asmussen, K. S., Muk (Mudi), Tik, Williams, Charlotte Amdi, Heegard, P., Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Nutrients. 13, 10, 3310.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide

    Christophersen, D. V., Jacobsen, N. R., Jensen, Ditte Marie, Kermanizadeh, A., Sheykhzade, Majid, Loft, Steffen, Vogel, U., Wallin, H. & Møller, Peter, 29 Aug 2016, In: P L o S One. 11, 8, p. 1-24 24 p., e0160731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Influence of R-R interval variations on the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 636-637 2 p., C-30.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  30. Published

    Influence of general anaesthesia on circulating biomarkers of glucose metabolism in pigs

    Christoffersen, B. Ø., Bundgaard, C. J., Hjøllund, K. R., Fels, J. J., Boll, K. K., Lyhne, Mille Kronborg & Olsen, Lisbeth Høier, 2023, In: Laboratory Animals. 57, 6, p. 650-663

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B., Nowak, J., Viuff, B. M., Rasmussen, C. L. M., Voetmann, Louise Marie, Fels, J. J., Madsen, S. H., McGuigan, F. E., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Akesson, K. E., 2020, In: Scientific Reports. 10, 1, 13 p., 5609.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes

    Andreasen, L. J., Kirk, R. K., Fledelius, C., Yorek, M. A., Lykkesfeldt, Jens & Akerstrom, T., 2020, In: Journal of Diabetes Research. 2020, 13 p., 9626398.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD

    Jensen, Victoria Svop, Fledelius, C., Zachodnik, C., Damgaard, J., Nygaard, H., Tornqvist, K. S., Kirk, R. K., Viuff, B. M., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Journal of Translational Medicine. 19, 1, 80.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs

    Christiansen, Line Iadsatian, Holmqvist, B., Pan, X., Holgersen, Kristine, Lindholm, S. E. H., Henriksen, Nicole Lind, Burrin, D. G., Ley, D., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: eNeuro. 10, 4, ENEURO.0430-22.2023.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Insulin-like growth factor 1 associated with altered immune responses in preterm infants and pigs

    Bæk, Ole, Rasmussen, Martin Bo, Gerts, T., Aunsholt, Lise, Zachariassen, G., Sangild, Per Torp & Nguyen, Duc Ninh, 2024, In: Pediatric Research. 95, p. 120–128 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs

    Christiansen, Line Iadsatian, Ventura, G. C., Holmqvist, B., Aasmul-Olsen, Karoline, Lindholm, S. E. H., Lycas, M. D., Mori, Yuki, Secher, Jan Bojsen-Møller, Burrin, D. G., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: Frontiers in Neuroscience. 17, 15 p., 1205819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Intrauterine growth restriction in piglets modulates postnatal immune function and hepatic transcriptional responses independently of energy intake

    Williams, Charlotte Amdi, Larsen, Christina, Jensen, K. M. R., Tange, E. Ø., Sato, Helena & Williams, Andrew Richard, 2023, In: Frontiers in Physiology. 14, 10 p., 1254958.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Investigation of noradrenergic receptor system in anti-nociception using formalin test in the naked mole rat (Heterocephalus glaber)

    Mwobobia, Royford, Kanui, T. I. & Abelson, Klas, Oct 2020, In: Heliyon. 6, 10, 6 p., e05216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Is sweet consumption under thirst and hunger really a good indicatior or depression?

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hestehave, S., 2022, In: Laboratory Animals. 56, S1, p. 25-26 S2A5.4.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    Late-onset Pompe disease is prevalent in unclassified limb-girdle muscular dystrophies

    Preisler, N., Lukacs, Z., Vinge, L., Madsen, K. L., Husu, E., Wils, Regitze Sølling, Duno, M., Andersen, H., Laub, M. S. H. & Vissing, John, 2013, In: Molecular Genetics and Metabolism. 110, 3, p. 287-289 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis

    Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

    Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Long term Westernized diet leads to region-specific changes in brain signaling mechanisms

    Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SKCa, IKCa, and Kir2.1 channels

    Gradel, Anna Katrina Jógvansdóttir, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik & Jensen, Lars Jørn, 28 Feb 2018, In: Clinical Science. 132, 4, p. 461–474 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Long-term excess fat and/or fructose ingestion causes changes in small artery K+ transporter expression and function with effects on blood pressure

    Gradel, Anna Katrina Jógvansdóttir, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik & Jensen, Lars Jørn, 22 Sep 2016. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  46. Published

    Longitudinal study on background lesions in broiler breeder flocks and their progeny, and genomic characterisation of Escherichia coli

    Kromann, Sofie, Baig, S., Stegger, M., Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2022, In: Veterinary Research. 53, 52.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets

    Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration

    Reimann, Maria Josefine, Haggstrom, J., Moller, J. E., Lykkesfeldt, Jens, Falk, T. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals

    Møller, Peter, Jensen, Ditte Marie, Christophersen, D. V., Kermanizadeh, A., Jacobsen, N. R., Hemmingsen, J. G., Danielsen, P. H., Karottki, D. G., Roursgaard, Martin, Cao, Y., Jantzen, K., Klingberg, H., Hersoug, L. & Loft, Steffen, Mar 2015, In: Environmental and Molecular Mutagenesis. 56, 2, p. 97-110 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

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