The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. Published

    Milk osteopontin for gut, immunity and brain development in preterm pigs

    Aasmul-Olsen, Karoline, Henriksen, Nicole Lind, Nguyen, Duc Ninh, Heckmann, A. B., Thymann, Thomas, Sangild, Per Torp & Bering, S. B., 2021, In: Nutrients. 13, 8, 2675.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels

    Reimann, Maria Josefine, Moller, J. E., Haggstrom, J., Martinussen, Torben, Zatrazemi, S. S. C., Svanholm, L., Nielsen, L. B. M., Pedersen, H. D. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 4, p. 1008-1016 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

    Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Modelling nonalcoholic steatohepatitis in vivo—a close transcriptomic similarity supports the guinea pig disease model

    Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Sep 2021, In: Biomedicines. 9, 9, 1198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Modulation of nociception by amitriptyline hydrochloride in the Speke’s hinge-back tortoise (Kiniskys spekii)

    Musembi Makau, Christopher, Towett, P. K., Abelson, Klas & Kanui, T. I., 2021, In: Veterinary Medicine and Science. 7, 3, p. 1034-1041

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Modulation of nociception by noradrenaline and serotonin receptor systems in speke’s hinge-back tortoise

    Musembi Makau, Christopher & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 128-129 PA15.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  7. Published

    Modulation of nociception by tricyclic antidepressants in the Speke’s hinge-back tortoise

    Musembi Makau, Christopher, 2022, Canadian Society for Brain, Behaviour, and Cognitive Science: CBBCS 2022 - 32nd Annual Meeting in Halifax, Nova Scotia. Halifax, Canada, p. 44-44

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review

  8. Published

    Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model

    Ipsen, David Højland, Skat-Rørdam, Josephine, Tsamouri, M. M., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Molecular Genetics and Genomics. 294, 3, p. 649–661

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    My journey towards higher education in laboratory animal science - a big thanks to European teaching and Laboratory Animals Limited (LAL) funding!

    Sreelatha, Harikrishnan Vijayakumar, 2022, In: Laboratory Animals. 56, 5, p. 491-492

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  11. Published

    Myxømatøs mitralklapsygdom hos hund: Metoder til diagnostik af behandlingskrævende sygdomsstadier

    Reimann, Maria Josefine, Christiansen, L. B., Falk, T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 9, p. 28-32

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

    Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Necrotizing enterocolitis is associated with acute brain responses in preterm pigs

    Sun, Jing, Pan, X., Christiansen, Line Iadsatian, Yuan, X., Skovgaard, K., Chatterton, Dereck Edward Winston, Kaalund, S. S., Gao, Fei, Sangild, Per Torp & Pankratova, Stanislava, 2018, In: Journal of Neuroinflammation. 15, 13 p., 180.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Neonatal prophylactic antibiotics after preterm birth affect plasma proteome and immune development in pigs

    Muk (Mudi), Tik, Leto, A., Brunse, Anders, Stensballe, A., Thymann, Thomas, Sangild, Per Torp & Nguyen, Duc Ninh, 2023, In: Pediatric Research. 94, p. 530–538

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response

    Reimann, Maria Josefine, Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, Signe Emilie, Møller, J. E., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Internal Medicine. 37, 6, p. 1947-2660

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

    Frederiksen, Henriette Reventlow S, Doehn, U., Tveden-Nyborg, Pernille & Freude, Kristine, 2021, In: Frontiers in Genome Editing. 2, 623717.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Normal Weight Dyslipidemia: Is It All About the Liver?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs

    Frederiksen, Henriette Reventlow S, Skov, Søren, Tveden-Nyborg, Pernille, Freude, Kristine & Doehn, U., 7 May 2024, In: Stem Cell Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Nutrient Fortification of Human Donor Milk Affects Intestinal Function and Protein Metabolism in Preterm Pigs

    Sun, Jing, Li, Y., Nguyen, Duc Ninh, Mortensen, M. S., van den Akker, C. H. P., Skeath, T., Pors, S. E., Pankratova, Stanislava, Rudloff, S., Sørensen, Søren Johannes, Burrin, D. G., Thymann, Thomas & Sangild, Per Torp, 2018, In: Journal of Nutrition. 148, 3, p. 336-347 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs

    Ahnfeldt, Agnethe May, Bæk, Ole, Hui, Y., Nielsen, Charlotte Holme, Obelitz-Ryom, K., Busk-Anderson, T., Ruge, A., Holst, Jens Juul, Rudloff, S., Burrin, D., Nguyen, Duc Ninh, Nielsen, Dennis Sandris, Zachariassen, G., Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2020, In: The Journal of Nutrition. 150, 5, p. 1196-1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs

    Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33 1 p., O11.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    Optimising the sampling procedure for forensic investigation of bruises on pigs

    Barington, Kristiane, Skovgaard, K., Henriksen, Nicole Lind & Jensen, Henrik Elvang, 2020, In: Veterinary Record. 187, 4, 153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir

    Pedersen, K., Gradel, Anna Katrina Jógvansdóttir, Ludvigsen, T. P., Christoffersen, B. Ø., Fuglsang-Damgaard, C. A., Bendtsen, K. M., Madsen, S. H., Manfé, V. & Refsgaard, H. H. F., 2022, In: Translational Research. 239, p. 71-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs

    di Ianni, Emilio, Møller, Peter, Mortensen, A., Szarek, J., Clausen, P. A., Saber, A. T., Vogel, U. & Jacobsen, N. R., 2020, In: Nanotoxicology. 14, 7, p. 869-892 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

    Møller, Peter, Danielsen, P. H., Karottki, D. G., Jantzen, K., Roursgaard, Martin, Klingberg, H., Jensen, Ditte Marie, Christophersen, D. V., Hemmingsen, J. G., Cao, Y. & Loft, Steffen, 2014, In: Mutation Research - Reviews. 762, p. 133-166 34 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Parasites and plants - bioactive compounds with anti-parasitic effect from Cichorium intybus

    Valente, Angela Hørdum, de Roode, B. M., Williams, Andrew Richard, Simonsen, H. T. & Thamsborg, Stig Milan, 2019, In: Planta Medica. 85, 18, p. 1420-1420

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  27. Published

    Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs

    Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, S. B. & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Perioperative nivolumab monotherapy versus nivolumab plus ipilimumab in resectable hepatocellular carcinoma: a randomised, open-label, phase 2 trial

    Kaseb, A. O., Hasanov, E., Cao, H. S. T., Xiao, L., Vauthey, J. N., Lee, S. S., Yavuz, B. G., Mohamed, Y. I., Qayyum, A., Jindal, S., Duan, F., Basu, S., Yadav, S. S., Nicholas, C., Sun, J. J., Singh Raghav, K. P., Rashid, A., Carter, K., Chun, Y. S., Tzeng, C. W. D. & 9 others, Sakamuri, D., Xu, L., Sun, R., Cristini, V., Beretta, L., Yao, J. C., Wolff, R. A., Allison, J. P. & Sharma, P., 2022, In: The Lancet Gastroenterology and Hepatology. 7, 3, p. 208-218 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Pharmacological safety of dimethoxy curcumin-human serum albumin conjugate for potential therapeutic purpose

    Korah, M. C., Sreelatha, Harikrishnan Vijayakumar, Deepa, S., Arya, A., Sabareeswaran, A., Mohanan, P. V. & Krishnan, L. K., 2023, In: Canadian Journal of Physiology and Pharmacology. 101, 6, p. 304-315

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Plasma and serum serotonin concentrations and surface-bound platelet serotonin expression in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2015, In: American Journal of Veterinary Research. 76, 6, p. 520-531 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Polymorphisms in the serotonin transporter gene do not associate with myxomatous mitral valve disease or circulating serotonin levels in Cavalier King Charles Spaniels

    Reimann, Maria Josefine, 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  33. Published

    Prenatal Intra-Amniotic Endotoxin Induces Fetal Gut and Lung Immune Responses and Postnatal Systemic Inflammation in Preterm Pigs

    Nguyen, Duc Ninh, Thymann, Thomas, Goericke-Pesch, S. K., Ren, S., Wei, W., Skovgaard, K., Damborg, Peter Panduro, Brunse, Anders, van Gorp, C., Kramer, B. W., Wolfs, T. G. & Sangild, Per Torp, 2018, In: American Journal of Pathology. 188, 11, p. 2629-2643 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Protective potential of an autogenous vaccine in an aerogenous model of escherichia coli infection in broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Vaccines. 9, 11, 1233.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013.

    Research output: Contribution to conference › Poster › Research

  36. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Randall Selitto pressure algometry for assessment of bone-related pain in rats

    Falk, S., Ipsen, David Højland, Appel, C. K., Ugarak, A., Durup, D., Dickenson, A. H. & Heegaard, Anne-Marie, 2015, In: European Journal of Pain. 19, 3, p. 305-312 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Rapid Postnatal Adaptation of Neurodevelopment in Pigs Born Late Preterm

    Nielsen, Charlotte Holme, Bladt Brandt, A., Thymann, Thomas, Obelitz-Ryom, K., Jiang, Pingping, Vanden Hole, C., van Ginneken, C., Pankratova, Stanislava & Sangild, Per Torp, 2019, In: Developmental Neuroscience. 40, 5-6, 15 p., 586–600.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Receptor Activator of Nuclear Factor kappa-B Ligand is Not Regulated During Chronic Osteomyelitis in Pigs

    Lüthje, F. L., Skovgaard, K., Jensen, Henrik Elvang, Blirup-Plum, Sophie Amalie, Henriksen, Nicole Lind, Aalbæk, Bent & Jensen, Louise Kruse, 2020, In: Journal of Comparative Pathology. 179, p. 7-24 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Reduced early life mucosal integrity decreases thymic cell counts and increases local, but not thymic regulatory, T cell recruitment: Gut mucosal integrity breach and thymic T cells

    Zakariassen, Hannah Louise, Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2019, In: European Journal of Inflammation. 17, p. 1-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Refinement of the motorised laminectomy-assisted rat spinal cord injury model by analgesic treatment

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2024, In: PLoS ONE. 19, 1 , 23 p., e0294720.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Refinement of the rat contusion model of thoracic spinal cord injury

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 27-27 S2B3.1.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  43. Published

    Refinement of the spinal cord injury rat model and validation of its applicability as a model for memory loss and chronic pain

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2021, In: Heliyon. 7, 7, 11 p., e07500.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Reliability of sucrose preference testing following short or no food and water deprivation—a Systematic Review and Meta-Analysis of rat models of chronic unpredictable stress

    Berrio Sanchez, Jenny Paola, Hestehave, Sara & Kalliokoski, Otto, 2024, In: Translational Psychiatry. 14, 1, 10 p., 39.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Rethinking data treatment: The sucrose preference threshold for anhedonia in stress-induced rat models of depression

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2023, In: Journal of Neuroscience Methods. 395, 11 p., 109910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)

    Brandt, S. D., Kavanagh, P. V., Westphal, F., Stratford, A., Odland, Anna Ulstein, Klein, A. K., Dowling, G., Dempster, N. M., Wallach, J., Passie, T. & Halberstadt, A. L., 2020, In: Drug Testing and Analysis. 12, p. 812-826

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research

    Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Role of oxidative stress in carbon nanotube-generated health effects

    Møller, P., Christophersen, D. V., Jensen, Ditte Marie, Kermanizadeh, A., Roursgaard, Martin, Jacobsen, N. R., Hemmingsen, J. G., Danielsen, P. H., Cao, Y., Jantzen, K., Klingberg, H., Hersoug, L. & Loft, Steffen, Nov 2014, In: Archives of Toxicology. 88, 11, p. 1939-64 26 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

    Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Searching for assay controls for the Fpg- and hOGG1-modified comet assay

    Møller, Peter, Jantzen, K., Løhr, M., Andersen, M. H., Jensen, Ditte Marie, Roursgaard, Martin, Danielsen, P. H., Jensen, Annie & Loft, Steffen, 24 Feb 2018, In: Mutagenesis. 33, 1, p. 9-19 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

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