The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. Published

    Milk osteopontin for gut, immunity and brain development in preterm pigs

    Aasmul-Olsen, Karoline, Henriksen, Nicole Lind, Nguyen, Duc Ninh, Heckmann, A. B., Thymann, Thomas, Sangild, Per Torp & Bering, S. B., 2021, In: Nutrients. 13, 8, 2675.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A Gently Processed Skim Milk-Derived Whey Protein Concentrate for Infant Formula: Effects on Gut Development and Immunity in Preterm Pigs

    Aasmul-Olsen, Karoline, Akıllıoğlu, H. G., Christiansen, Line Iadsatian, Engholm-Keller, Kasper, Brunse, Anders, Stefanova, Denitsa Vladimirova, Bjørnshave, A., Bechshøft, M. R., Skovgaard, K., Thymann, Thomas, Sangild, Per Torp, Lund, Marianne N. & Bering, S. B., 2024, In: Molecular Nutrition and Food Research. 68, 6, 2300458.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    FortiColos - A multicentre study using bovine colostrum as a fortifier to human milk in very preterm infants: Study protocol for a randomised controlled pilot trial

    Ahnfeldt, Agnethe May, Hyldig, N., Li, Y., Kappel, S. S., Aunsholdt, L., Sangild, Per Torp & Zachariassen, G., 2019, In: Trials. 20, 9 p., 279.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs

    Ahnfeldt, Agnethe May, Bæk, Ole, Hui, Y., Nielsen, Charlotte Holme, Obelitz-Ryom, K., Busk-Anderson, T., Ruge, A., Holst, Jens Juul, Rudloff, S., Burrin, D., Nguyen, Duc Ninh, Nielsen, Dennis Sandris, Zachariassen, G., Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2020, In: The Journal of Nutrition. 150, 5, p. 1196-1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Bovine colostrum as a fortifier to human milk in very preterm infants – A randomized controlled trial (FortiColos)

    Ahnfeldt, Agnethe May, Aunsholt, Lise, Hansen, Bo Mølholm, Hoest, B., Jóhannsdóttir, V., Kappel, S. S., Klamer, A., Möller, S., Moeller, B. K., Sangild, Per Torp, Skovgaard, A. L., van Hall, Gerrit, Vibede, L. D. & Zachariassen, G., 2023, In: Clinical Nutrition. 42, 5, p. 773-783 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Suckling Induces Differential Gut Enzyme Activity and Body Composition Compared to Feeding Milk Replacer in Piglets

    Williams, Charlotte Amdi, Pedersen, M. L. M., Larsen, Christina, Klaaborg, J., Williams, Andrew Richard & Madsen, Johannes Gulmann, 2022, In: Animals. 12, 22, 3112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Health effects of exposure to diesel exhaust in diesel-powered trains

    Andersen, M. H. G., Frederiksen, M., Saber, A. T., Wils, Regitze Sølling, Fonseca, A. S., Koponen, I. K., Johannesson, S., Roursgaard, Martin, Loft, Steffen, Møller, Peter & Vogel, U., 2019, In: Particle and Fibre Toxicology. 16, 14 p., 21.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Creatine kinase response to high-intensity aerobic exercise in adult-onset muscular dystrophy

    Andersen, S. P., Sveen, M., Wils, Regitze Sølling, Madsen, K. L., Hansen, J. B., Madsen, M. L. & Vissing, John, 2013, In: Muscle & Nerve. 48, 6, p. 897-901 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes

    Andreasen, L. J., Kirk, R. K., Fledelius, C., Yorek, M. A., Lykkesfeldt, Jens & Akerstrom, T., 2020, In: Journal of Diabetes Research. 2020, 13 p., 9626398.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Finding new analgesics: Computational pharmacology faces drug discovery challenges

    Barakat, Ahmed, Munro, G. & Heegaard, Anne-Marie, 2024, In: Biochemical Pharmacology. 222, 21 p., 116091.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Optimising the sampling procedure for forensic investigation of bruises on pigs

    Barington, Kristiane, Skovgaard, K., Henriksen, Nicole Lind & Jensen, Henrik Elvang, 2020, In: Veterinary Record. 187, 4, 153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    [68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction

    Bentsen, Simon, Clemmensen, Andreas Høeg, Loft, Mathias Hougaard, Flethøj, M., Debes, Karina Poulsdóttir, Ludvigsen, Trine Pagh, Larsen, C. B., Kirchhoff, J., Olsen, Lisbeth Høier, Møller, J. E., Andersen, Thomas Lund, Johannesen, Helle Hjorth, Jespersen, Thomas & Kjær, Andreas, 2021, In: Diagnostics. 11, 10, 1807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effects of Transdermal Fentanyl Treatment on Acute Pain and Inflammation in Rats with Adjuvant-induced Monoarthritis

    Berke, M. S., Colding-Jørgensen, Pernille, Pedersen, L. G., Hestehave, Sara, Kalliokoski, Otto, Jensen, Henrik Elvang, Sørensen, Dorte Bratbo, Hau, Jann & Abelson, Klas, 2022, In: Comparative Medicine. 72, 5, p. 320–329 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model

    Berke, M. S., Fensholdt, L. K. D., Hestehave, Sara, Kalliokoski, Otto & Abelson, Klas, Jan 2022, In: PLoS ONE. 17, 1, 21 p., e0260356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The adjuvant-induced rat model of monoarthritis: welfare implications and possible refinement strategies

    Berke, M. S. & Abelson, Klas, 2020, In: Scandinavian Journal of Laboratory Animal Science. 46, 5, p. 39-50 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Buprenorphine alleviation of pain does not compromise the rat monoarthritic pain model

    Berke, M. S. & Abelson, Klas, 2017, In: Scandinavian Journal of Pain. 16, p. 167-167 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  17. Published

    Reliability of sucrose preference testing following short or no food and water deprivation—a Systematic Review and Meta-Analysis of rat models of chronic unpredictable stress

    Berrio Sanchez, Jenny Paola, Hestehave, Sara & Kalliokoski, Otto, 2024, In: Translational Psychiatry. 14, 1, 10 p., 39.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Rethinking data treatment: The sucrose preference threshold for anhedonia in stress-induced rat models of depression

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2023, In: Journal of Neuroscience Methods. 395, 11 p., 109910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    We need to talk about fraudulent animal studies: learnings from a systematic review

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2022, In: Laboratory Animals. 56, S1, p. 172-172 PD15.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  20. Published

    Fighting Irreproducibility in Preclinical Neuroscience Using a Meta-analytical Approach: The Case of the Chronic Unpredictable Stress Model of Depression

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hau, Jann, 2023, University of Copenhagen. 80 p.

    Research output: Book/Report › Ph.D. thesis › Research

  21. Published

    Is sweet consumption under thirst and hunger really a good indicatior or depression?

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hestehave, S., 2022, In: Laboratory Animals. 56, S1, p. 25-26 S2A5.4.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    Evaluation of the breeding program aiming at reducing the prevalence of myxomatous mitral valve disease in Cavalier King Charles Spaniels in Denmark

    Birkegaard , A. C., Reimann, Maria Josefine, Häggström, J., Martinussen, Torben, Pedersen , H. D. & Olsen, Lisbeth Høier, 2013, American College of Veterinary Internal Medicine, Congress Proceedings. Sellon, R. K. & McClure, J. T. (eds.). Lakewood, p. 172 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  23. Published

    Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8-to 10-Year Period

    Birkegård, A. C., Reimann, Maria Josefine, Martinussen, Torben, Haggstrom, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2016, In: Journal of Veterinary Internal Medicine. 30, 1, p. 63-68 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

    Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree

    Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Decreased expression of the GLP-1 receptor after segmental artery injury in mice

    Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Dietary seaweed (Saccharina latissima) supplementation in pigs induces localized immunomodulatory effects and minor gut microbiota changes during intestinal helminth infection

    Bonde, C. S., Mejer, Helena, Myhill, Laura Jessica, Zhu, L., Jensen, Penille, Büdeyri Gökgöz, Nilay, Krych, Lukasz, Nielsen, Dennis Sandris, Skovgaard, K., Thamsborg, Stig Milan & Williams, Andrew Richard, 2023, In: Scientific Reports. 13, 16 p., 21931.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)

    Brandt, S. D., Kavanagh, P. V., Westphal, F., Stratford, A., Odland, Anna Ulstein, Klein, A. K., Dowling, G., Dempster, N. M., Wallach, J., Passie, T. & Halberstadt, A. L., 2020, In: Drug Testing and Analysis. 12, p. 812-826

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Increased meal-induced neurotensin response predicts successful maintenance of weight loss: Data from a randomized controlled trial

    Brethvad, Annemette Overgaard, Zakariassen, Hannah Louise, Holt, Joachim, Lundgren, J. R., Jakobsen, A., Hartmann, Bolette, Lehmann, E. W., Kissow, Hannelouise, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Holst, Birgitte, 2023, In: Metabolism: Clinical and Experimental. 143, 8 p., 155534.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Fecal filtrate transplantation protects against necrotizing enterocolitis

    Brunse, Anders, Deng, Ling, Pan, X., Hui, Y., Castro Mejia, J. L., Kot, Witold, Nguyen, Duc Ninh, Secher, Jan Bojsen-Møller, Nielsen, Dennis Sandris & Thymann, Thomas, 2022, In: The ISME Journal. 16, p. 686–694

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Enteral broad-spectrum antibiotics antagonize the effect of fecal microbiota transplantation in preterm pigs

    Brunse, Anders, Offersen, Simone Margaard, Mosegaard, J. J., Deng, Ling, Damborg, Peter Panduro, Nielsen, Dennis Sandris, Sangild, Per Torp, Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Gut Microbes. 13, 1, p. 1-16 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    FECAL MICROBIOTA TRANSPLANTATION PROTECTS AGAINST NECROTIZING ENTEROCOLITIS BUT INCREASES OVERALL MORTALITY IN PRETERM NEWBORN PIGS

    Brunse, Anders, Martin, L., Cilieborg, Malene Skovsted, Christensen, Lars, Thymann, Thomas, Pieper, R. & Sangild, Per Torp, Nov 2016, In: European Journal of Pediatrics. 175, 11, p. 1731-1732 2 p., 922 EAPS-0605.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  34. Published

    Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels

    Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    EARLY ENTERAL FEEDING REDUCES SEPSIS RESPONSE AND NEUROINFLAMMATION IN A PIG MODEL OF NEONATAL BLOODSTREAM INFECTION

    Brunse, Anders, Worsøe, P. S., Pors, S. E., Skovgaard, K. & Sangild, Per Torp, Nov 2016, In: European Journal of Pediatrics. 175, 11, p. 1497-1497 1 p., 307, EAPS-0930.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  36. Published

    Brain Barrier Disruption and Region-Specific Neuronal Degeneration during Necrotizing Enterocolitis in Preterm Pigs

    Brunse, Anders, Abbaspour, A. & Sangild, Per Torp, 1 Oct 2018, In: Developmental Neuroscience. 40, 3, p. 198–208

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The effect of feeding liquid or dry creep feed on growth performance, feed disappearance, enzyme activity and number of eaters in suckling piglets

    Byrgesen, N., Madsen, Johannes Gulmann, Larsen, Christina, Kjeldsen, N. J., Cilieborg, Malene Skovsted & Williams, Charlotte Amdi, 2021, In: Animals. 11, 11, 3144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Diet Modulates the High Sensitivity to Systemic Infection in Newborn Preterm Pigs

    Bæk, Ole, Brunse, Anders, Nguyen, Duc Ninh, Moodley, Arshnee, Thymann, Thomas & Sangild, Per Torp, 2020, In: Frontiers in Immunology. 11, 14 p., 1019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Insulin-like growth factor 1 associated with altered immune responses in preterm infants and pigs

    Bæk, Ole, Rasmussen, Martin Bo, Gerts, T., Aunsholt, Lise, Zachariassen, G., Sangild, Per Torp & Nguyen, Duc Ninh, 2024, In: Pediatric Research. 95, p. 120–128 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Sex-Specific Survival, Growth, Immunity and Organ Development in Preterm Pigs as Models for Immature Newborns

    Bæk, Ole, Cilieborg, Malene Skovsted, Nguyen, Duc Ninh, Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 12 p., 626101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Growth Restriction and Systemic Immune Development in Preterm Piglets

    Bæk, Ole, Sangild, Per Torp, Thymann, Thomas & Nguyen, Duc Ninh, 2019, In: Frontiers in Immunology. 10, 2402.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Infant Formula Based on Milk Fat Affects Immune Development in Both Normal Birthweight and Fetal Growth Restricted Neonatal Piglets

    Bæk, Ole, Asmussen, K. S., Muk (Mudi), Tik, Williams, Charlotte Amdi, Heegard, P., Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Nutrients. 13, 10, 3310.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets

    Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Impaired Neonatal Immunity and Infection Resistance Following Fetal Growth Restriction in Preterm Pigs

    Bæk, Ole, Ren, S., Brunse, Anders, Sangild, Per Torp & Nguyen, Duc Ninh, 2020, In: Frontiers in Immunology. 11, 1808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Gabor patterns as stimuli in a rodent visual attention task

    Caballero-Puntiverio, M., Prichardt, S., Klem, Louise Bomholt, Bundesen, C., Vangkilde, Signe & Andreasen T., Jesper, 2020, In: Neuroscience Letters. 728, 8 p., 134970.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs

    Christiansen, Line Iadsatian, Ventura, G. C., Holmqvist, B., Aasmul-Olsen, Karoline, Lindholm, S. E. H., Lycas, M. D., Mori, Yuki, Secher, Jan Bojsen-Møller, Burrin, D. G., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: Frontiers in Neuroscience. 17, 15 p., 1205819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs

    Christiansen, Line Iadsatian, Holmqvist, B., Pan, X., Holgersen, Kristine, Lindholm, S. E. H., Henriksen, Nicole Lind, Burrin, D. G., Ley, D., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: eNeuro. 10, 4, ENEURO.0430-22.2023.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

    Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Influence of general anaesthesia on circulating biomarkers of glucose metabolism in pigs

    Christoffersen, B. Ø., Bundgaard, C. J., Hjøllund, K. R., Fels, J. J., Boll, K. K., Lyhne, Mille Kronborg & Olsen, Lisbeth Høier, 2023, In: Laboratory Animals. 57, 6, p. 650-663

    Research output: Contribution to journal › Journal article › Research › peer-review

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