The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. 2020
  2. Published

    Impaired Neonatal Immunity and Infection Resistance Following Fetal Growth Restriction in Preterm Pigs

    Bæk, Ole, Ren, S., Brunse, Anders, Sangild, Per Torp & Nguyen, Duc Ninh, 2020, In: Frontiers in Immunology. 11, 1808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B., Nowak, J., Viuff, B. M., Rasmussen, C. L. M., Voetmann, Louise Marie, Fels, J. J., Madsen, S. H., McGuigan, F. E., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Akesson, K. E., 2020, In: Scientific Reports. 10, 1, 13 p., 5609.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes

    Andreasen, L. J., Kirk, R. K., Fledelius, C., Yorek, M. A., Lykkesfeldt, Jens & Akerstrom, T., 2020, In: Journal of Diabetes Research. 2020, 13 p., 9626398.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets

    Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs

    Ahnfeldt, Agnethe May, Bæk, Ole, Hui, Y., Nielsen, Charlotte Holme, Obelitz-Ryom, K., Busk-Anderson, T., Ruge, A., Holst, Jens Juul, Rudloff, S., Burrin, D., Nguyen, Duc Ninh, Nielsen, Dennis Sandris, Zachariassen, G., Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2020, In: The Journal of Nutrition. 150, 5, p. 1196-1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Optimising the sampling procedure for forensic investigation of bruises on pigs

    Barington, Kristiane, Skovgaard, K., Henriksen, Nicole Lind & Jensen, Henrik Elvang, 2020, In: Veterinary Record. 187, 4, 153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs

    di Ianni, Emilio, Møller, Peter, Mortensen, A., Szarek, J., Clausen, P. A., Saber, A. T., Vogel, U. & Jacobsen, N. R., 2020, In: Nanotoxicology. 14, 7, p. 869-892 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Polymorphisms in the serotonin transporter gene do not associate with myxomatous mitral valve disease or circulating serotonin levels in Cavalier King Charles Spaniels

    Reimann, Maria Josefine, 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  10. Published

    Receptor Activator of Nuclear Factor kappa-B Ligand is Not Regulated During Chronic Osteomyelitis in Pigs

    Lüthje, F. L., Skovgaard, K., Jensen, Henrik Elvang, Blirup-Plum, Sophie Amalie, Henriksen, Nicole Lind, Aalbæk, Bent & Jensen, Louise Kruse, 2020, In: Journal of Comparative Pathology. 179, p. 7-24 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)

    Brandt, S. D., Kavanagh, P. V., Westphal, F., Stratford, A., Odland, Anna Ulstein, Klein, A. K., Dowling, G., Dempster, N. M., Wallach, J., Passie, T. & Halberstadt, A. L., 2020, In: Drug Testing and Analysis. 12, p. 812-826

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

    Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Brockhoff, P. M. B., Seested, T. & Refsgaard, H. H. F., 2020, In: Experimental and Clinical Endocrinology and Diabetes. 128, 5, p. 332-338 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice

    Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The adjuvant-induced rat model of monoarthritis: welfare implications and possible refinement strategies

    Berke, M. S. & Abelson, Klas, 2020, In: Scandinavian Journal of Laboratory Animal Science. 46, 5, p. 39-50 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

    Jensen, Anders A., Halberstadt, A. L., Marcher, Emil, Odland, Anna Ulstein, Chatha, M., Speth, N., Liebscher, G., Hansen, M., Bräuner, Hans, Palner, M., Andreasen T., Jesper & Kristensen, Jesper Langgaard, 2020, In: Biochemical Pharmacology. 177, 16 p., 113979.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models

    Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Imiquimod does not elicit inflammatory responses in the skin of the naked mole rat (Heterocephalus glaber)

    Kisipan, Mosiany Letura, Ojoo, R. O., Kanui, T. I. & Abelson, Klas, 5 Sep 2020, In: BMC Research Notes. 13, 6 p., 416.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Investigation of noradrenergic receptor system in anti-nociception using formalin test in the naked mole rat (Heterocephalus glaber)

    Mwobobia, Royford, Kanui, T. I. & Abelson, Klas, Oct 2020, In: Heliyon. 6, 10, 6 p., e05216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The counterregulatory response to hypoglycaemia in the pig

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Ludvigsen, T. P., Porsgaard, T., Schou-Pedersen, A. M. V., Fels, J. J., Lykkesfeldt, Jens & Refsgaard, H. H. F., Oct 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 278-286

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2021
  22. Published

    A reduced CP level without medicinal zinc oxide does not alter the intestinal morphology in weaned pigs 24 days post-weaning

    Larsen, Christina, Lynegaard, J. C., Pedersen, Anni Øyan, Kjeldsen, N. J., Hansen, C. F., Nielsen, Jens Peter & Williams, Charlotte Amdi, 2021, In: Animal. 15, 4, 100188.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A report on less-severe, long-duration persistent hind-limb ischemia surgical rabbit model

    Sreelatha, Harikrishnan Vijayakumar, Shenoy, S. J., Ranaraj, V. R., Sukhija, S. & Oloyo, A. K., 2021, In: Journal of the Hellenic Veterinary Medical Society. 72, 4, p. 3455-3462 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree

    Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

    Lindenberg, F. C., Lützhøft, Ditte Olsen, Krych, Lukasz, Fielden, J., Kot, Witold, Frøkiær, Hanne, van Galen, G., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Frontiers in Microbiology. 12, 666039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels

    Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

    Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, S. B. & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Decreased expression of the GLP-1 receptor after segmental artery injury in mice

    Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

    Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Development of an aerogenous Escherichia coli infection model in adult broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Scientific Reports. 11, 15 p., 19556.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis

    Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Enteral broad-spectrum antibiotics antagonize the effect of fecal microbiota transplantation in preterm pigs

    Brunse, Anders, Offersen, Simone Margaard, Mosegaard, J. J., Deng, Ling, Damborg, Peter Panduro, Nielsen, Dennis Sandris, Sangild, Per Torp, Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Gut Microbes. 13, 1, p. 1-16 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Extracellular vesicles as drivers of non-alcoholic fatty liver disease: Small particles with big impact

    Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 1, p. 1-13 13 p., 93.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Porsgaard, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 6, p. 783-794

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis—Roles as Putative Treatment Targets?

    Zisser, Alexandra, Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 4, 365.

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    Hyperinsulinaemic hypoglycaemia in non-anaesthetized Göttingen minipigs induces a counter-regulatory endocrine response and electrocardiographic changes

    Lyhne, Mille Kronborg, Vegge, A., Povlsen, G. K., Slaaby, R., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2021, In: Scientific Reports. 11, 11 p., 5983.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Identification of compounds responsible for the anthelmintic effects of chicory (Cichorium intybus) by molecular networking and bio-guided fractionation

    Valente, Angela Hørdum, de Roode, M., Ernst, M., Peña-Espinoza, M., Bornancin, L., Bonde, C. S., Martínez-Valladares, M., Ramünke, S., Krücken, J., Simonsen, H. T., Thamsborg, Stig Milan & Williams, Andrew Richard, 2021, In: International Journal for Parasitology: Drugs and Drug Resistance. 15, p. 105-114 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Infant Formula Based on Milk Fat Affects Immune Development in Both Normal Birthweight and Fetal Growth Restricted Neonatal Piglets

    Bæk, Ole, Asmussen, K. S., Muk (Mudi), Tik, Williams, Charlotte Amdi, Heegard, P., Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Nutrients. 13, 10, 3310.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD

    Jensen, Victoria Svop, Fledelius, C., Zachodnik, C., Damgaard, J., Nygaard, H., Tornqvist, K. S., Kirk, R. K., Viuff, B. M., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Journal of Translational Medicine. 19, 1, 80.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

    Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Milk osteopontin for gut, immunity and brain development in preterm pigs

    Aasmul-Olsen, Karoline, Henriksen, Nicole Lind, Nguyen, Duc Ninh, Heckmann, A. B., Thymann, Thomas, Sangild, Per Torp & Bering, S. B., 2021, In: Nutrients. 13, 8, 2675.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

    Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Modulation of nociception by amitriptyline hydrochloride in the Speke’s hinge-back tortoise (Kiniskys spekii)

    Musembi Makau, Christopher, Towett, P. K., Abelson, Klas & Kanui, T. I., 2021, In: Veterinary Medicine and Science. 7, 3, p. 1034-1041

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

    Frederiksen, Henriette Reventlow S, Doehn, U., Tveden-Nyborg, Pernille & Freude, Kristine, 2021, In: Frontiers in Genome Editing. 2, 623717.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Protective potential of an autogenous vaccine in an aerogenous model of escherichia coli infection in broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Vaccines. 9, 11, 1233.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Refinement of the spinal cord injury rat model and validation of its applicability as a model for memory loss and chronic pain

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2021, In: Heliyon. 7, 7, 11 p., e07500.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Sex-Specific Survival, Growth, Immunity and Organ Development in Preterm Pigs as Models for Immature Newborns

    Bæk, Ole, Cilieborg, Malene Skovsted, Nguyen, Duc Ninh, Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 12 p., 626101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Temporal development of dyslipidemia and nonalcoholic fatty liver disease (Nafld) in syrian hamsters fed a high‐fat, high‐fructose, high‐cholesterol diet

    Jensen, Victoria Svop, Fledelius, C., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Nutrients. 13, 2, p. 1-18 18 p., 604.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs

    Ipsen, David Højland, Agerskov, R. H., Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Scientific Reports. 11, 2955.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis

    Ipsen, David Højland, Skat-Rørdam, Josephine, Svenningsen, M., Andersen, Mia Trein, Latta, M., Buelund, Lene Elisabeth, Lintrup, K., Skaarup, R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 4, p. 583-593

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    The effect of feeding liquid or dry creep feed on growth performance, feed disappearance, enzyme activity and number of eaters in suckling piglets

    Byrgesen, N., Madsen, Johannes Gulmann, Larsen, Christina, Kjeldsen, N. J., Cilieborg, Malene Skovsted & Williams, Charlotte Amdi, 2021, In: Animals. 11, 11, 3144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The selective 5-HT2A receptor agonist 25CN-NBOH does not affect reversal learning in mice

    Odland, Anna Ulstein, Kristensen, Jesper Langgaard & Andreasen T., Jesper, 2021, In: Behavioural Pharmacology. 32, 5, p. 448-452

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    [68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction

    Bentsen, Simon, Clemmensen, Andreas Høeg, Loft, Mathias Hougaard, Flethøj, M., Debes, Karina Poulsdóttir, Ludvigsen, Trine Pagh, Larsen, C. B., Kirchhoff, J., Olsen, Lisbeth Høier, Møller, J. E., Andersen, Thomas Lund, Johannesen, Helle Hjorth, Jespersen, Thomas & Kjær, Andreas, 2021, In: Diagnostics. 11, 10, 1807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    High Parenteral Support Volume Is Associated With Reduced Quality of Life Determined by the Short‐Bowel Syndrome Quality of Life Scale in Nonmalignant Intestinal Failure Patients

    Nordsten, C. B., Mølsted, Stig, Bangsgaard, L., Fuglsang, K. A., Brandt, C. F., Niemann, Mads Jacob & Jeppesen, Palle Bekker, 1 Jul 2021, In: Journal of Parenteral and Enteral Nutrition. 45, 5, p. 926-932 7 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  56. Published

    Modelling nonalcoholic steatohepatitis in vivo—a close transcriptomic similarity supports the guinea pig disease model

    Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Sep 2021, In: Biomedicines. 9, 9, 1198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2022
  58. Published

    In vivo models of Escherichia coli infection in poultry

    Kromann, Sofie & Jensen, Henrik Elvang, 2022, In: Acta Veterinaria Scandinavica. 64, 33.

    Research output: Contribution to journal › Review › Research › peer-review

  59. Published

    A Randomized, Controlled Study to Investigate How Bovine Colostrum Fortification of Human Milk Affects Bowel Habits in Preterm Infants (FortiColos Study)

    Kappel, S. S., Sangild, Per Torp, Ahnfeldt, Agnethe May, Johannsdottir, V., Soernsen, L. J., Bak, L. B., Friborg, C., Moller, S., Zachariassen, G. & Aunsholt, Lise, 2022, In: Nutrients. 14, 22, 14 p., 4756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study

    Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Anti-protozoal activity and metabolomic analyses of Cichorium intybus L. against Trypanosoma cruzi

    Peña-Espinoza, M., Romero-Uzqueda, Y., Valente, Angela Hørdum, de Roode, M., Simonsen, H. T., Thamsborg, Stig Milan, Williams, Andrew Richard & López-Muñoz, R., 2022, In: International Journal for Parasitology: Drugs and Drug Resistance. 20, p. 43-53 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Assessment of automated assays for serum amyloid A, haptoglobin (PIT54) and basic biochemistry in broiler breeders experimentally infected with Escherichia coli

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2022, In: Veterinary Research. 53, 1, 7 p., 25.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Bodyweight, locomotion, and behavioral responses in the naked mole-rat (heterocephalus glaber) after lipopolysaccharide administration

    Kisipan, Mosiany Letura, Ojoo, R. O., Kanui, T. I. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 191-191 PE21.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  64. Published

    Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets

    Henriksen, Nicole Lind, Asmussen, K. S., Pan, X., Jiang, Pingping, Mori, Yuki, Christiansen, Line Iadsatian, Sprenger, R. R., Ejsing, C. S., Pankratova, Stanislava & Thymann, Thomas, 2022, In: Scientific Reports. 12, 1, 3303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    CTLA4-Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats

    Øvlisen, Gabi Overgaard, Thygesen, P., Weldingh, K. N., Bloem, E., Skov, Søren, Almholt, K., Lövgren, K. M., Ley, C. D. & Holm, T. L., 2022, In: Haemophilia. 28, 4, p. 568-577

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Clinical outcome and gut development after insulin-like growth factor-1 supplementation to preterm pigs

    Holgersen, Kristine, Rasmussen, Martin Bo, Carey, G., Burrin, D. G., Thymann, Thomas & Sangild, Per Torp, 2022, In: Frontiers in Pediatrics. 10, 868911.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Colibacillosis in poultry: Aetiology, pathogenesis, diagnosis, and control

    Kromann, Sofie, 2022, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  68. Published

    Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs

    Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Donor-dependent fecal microbiota transplantation efficacy against necrotizing enterocolitis in preterm pigs

    Hui, Y., Vestergaard, G., Deng, Ling, Kot, Witold, Thymann, Thomas, Brunse, Anders & Nielsen, Dennis Sandris, 2022, In: npj Biofilms and Microbiomes. 8, 1, 12 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Effect of the sodium-glucose cotransporter-2 inhibitor dapagliflozinon platelet aggregation response in Cavalier King Charles Spanielswith and without cardiac disease

    Speitzer, A., Øgelund, E., Reimann, Maria Josefine, Møller, J. E., Skovsted, G. F., Lyhne, Mille Kronborg, Verma, S., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 2473 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  71. Published

    Effects of Transdermal Fentanyl Treatment on Acute Pain and Inflammation in Rats with Adjuvant-induced Monoarthritis

    Berke, M. S., Colding-Jørgensen, Pernille, Pedersen, L. G., Hestehave, Sara, Kalliokoski, Otto, Jensen, Henrik Elvang, Sørensen, Dorte Bratbo, Hau, Jann & Abelson, Klas, 2022, In: Comparative Medicine. 72, 5, p. 320–329 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Effects of anti-inflammatory drugs on induced chronic Inflammation in the naked mole rat

    Thuo, Jesse Kevin Ndung´u, Towett, P., Kanui, T. I. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 131-132 PA24.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  73. Published

    Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

    Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Electrocardiography and heart rate variability in Göttingen Minipigs: Impact of diurnal variation, lead placement, repeatability and streptozotocin-induced diabetes

    Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Helgogaard, T., Vegge, A., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 107221.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Empirical study of bias in a rat model of rheumatoid arthritis (RA)

    Seveljevic-Jaran, Dasa, Hau, Jann, Abelson, Klas & Kalliokoski, Otto, 2022, University of Copenhagen. 91 p.

    Research output: Book/Report › Ph.D. thesis › Research

  76. Published

    Fecal filtrate transplantation protects against necrotizing enterocolitis

    Brunse, Anders, Deng, Ling, Pan, X., Hui, Y., Castro Mejia, J. L., Kot, Witold, Nguyen, Duc Ninh, Secher, Jan Bojsen-Møller, Nielsen, Dennis Sandris & Thymann, Thomas, 2022, In: The ISME Journal. 16, p. 686–694

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Fibrous dysplasia animal models: A systematic review

    Hopkins, Chelsea, de Castro, L. F., Corsi, A., Boyce, A., Collins, M. T., Riminucci, M. & Heegaard, Anne-Marie, 2022, In: Bone. 155, 13 p., 116270.

    Research output: Contribution to journal › Review › Research › peer-review

  78. Published

    Glucose supply and glycolysis inhibition shape the clinical fate of Staphylococcus epidermidis-infected preterm newborns

    Muk (Mudi), Tik, Brunse, Anders, Henriksen, Nicole Lind, Aasmul-Olsen, Karoline & Nguyen, Duc Ninh, 2022, In: JCI Insight. 7, 11, 18 p., e157234.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function

    Voetmann, Louise Marie, Underwood, C. R., Rolin, B., Hansen, Axel Kornerup, Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Is sweet consumption under thirst and hunger really a good indicatior or depression?

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hestehave, S., 2022, In: Laboratory Animals. 56, S1, p. 25-26 S2A5.4.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  81. Published

    Longitudinal study on background lesions in broiler breeder flocks and their progeny, and genomic characterisation of Escherichia coli

    Kromann, Sofie, Baig, S., Stegger, M., Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2022, In: Veterinary Research. 53, 52.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Modulation of nociception by noradrenaline and serotonin receptor systems in speke’s hinge-back tortoise

    Musembi Makau, Christopher & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 128-129 PA15.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  84. Published

    Modulation of nociception by tricyclic antidepressants in the Speke’s hinge-back tortoise

    Musembi Makau, Christopher, 2022, Canadian Society for Brain, Behaviour, and Cognitive Science: CBBCS 2022 - 32nd Annual Meeting in Halifax, Nova Scotia. Halifax, Canada, p. 44-44

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review

  85. Published

    My journey towards higher education in laboratory animal science - a big thanks to European teaching and Laboratory Animals Limited (LAL) funding!

    Sreelatha, Harikrishnan Vijayakumar, 2022, In: Laboratory Animals. 56, 5, p. 491-492

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  86. Published

    Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir

    Pedersen, K., Gradel, Anna Katrina Jógvansdóttir, Ludvigsen, T. P., Christoffersen, B. Ø., Fuglsang-Damgaard, C. A., Bendtsen, K. M., Madsen, S. H., Manfé, V. & Refsgaard, H. H. F., 2022, In: Translational Research. 239, p. 71-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Perioperative nivolumab monotherapy versus nivolumab plus ipilimumab in resectable hepatocellular carcinoma: a randomised, open-label, phase 2 trial

    Kaseb, A. O., Hasanov, E., Cao, H. S. T., Xiao, L., Vauthey, J. N., Lee, S. S., Yavuz, B. G., Mohamed, Y. I., Qayyum, A., Jindal, S., Duan, F., Basu, S., Yadav, S. S., Nicholas, C., Sun, J. J., Singh Raghav, K. P., Rashid, A., Carter, K., Chun, Y. S., Tzeng, C. W. D. & 9 others, Sakamuri, D., Xu, L., Sun, R., Cristini, V., Beretta, L., Yao, J. C., Wolff, R. A., Allison, J. P. & Sharma, P., 2022, In: The Lancet Gastroenterology and Hepatology. 7, 3, p. 208-218 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Refinement of the rat contusion model of thoracic spinal cord injury

    Sreelatha, Harikrishnan Vijayakumar, Palekkodan, H., Fasaludeen, A., Krishnan, L. K. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 27-27 S2B3.1.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  89. Published

    Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation

    Jensen, Ditte Marie, Skovsted, Gry Freja, Bonde, M. F. B., Bentzon, J. F., Rolin, B., Franck, G., Ougaard, M. K. E., Voetmann, Louise Marie, Bachmann, J. C., Uryga, A., Pyke, C., Kirk, R. K., Hvid, H., Knudsen, L. B., Lykkesfeldt, Jens & Nyberg, M., 2022, In: Atherosclerosis Plus. 49, p. 32-41 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Suckling Induces Differential Gut Enzyme Activity and Body Composition Compared to Feeding Milk Replacer in Piglets

    Williams, Charlotte Amdi, Pedersen, M. L. M., Larsen, Christina, Klaaborg, J., Williams, Andrew Richard & Madsen, Johannes Gulmann, 2022, In: Animals. 12, 22, 3112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain

    Zhang, X. Y., Barakat, Ahmed, Diaz-delCastillo, M., Vollert, J., Sena, E. S., Heegaard, Anne-Marie, Rice, A. S. C. & Soliman, N., 2022, In: Pain. 163, 11, p. 2076-2102

    Research output: Contribution to journal › Review › Research › peer-review

  92. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Ultra-High Temperature Treatment and Storage of Infant Formula Induces Dietary Protein Modifications, Gut Dysfunction, and Inflammation in Preterm Pigs

    Sun, Jing, Akıllıoğlu, H. G., Aasmul-Olsen, Karoline, Ye, Y., Lund, P., Zhao, X., Brunse, Anders, Nielsen, C. F., Chatterton, Dereck Edward Winston, Sangild, Per Torp, Lund, Marianne N. & Bering, S. B., 2022, In: Molecular Nutrition & Food Research. 66, 20, 13 p., 2200132.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

    Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig

    Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    We need to talk about fraudulent animal studies: learnings from a systematic review

    Berrio Sanchez, Jenny Paola & Kalliokoski, Otto, 2022, In: Laboratory Animals. 56, S1, p. 172-172 PD15.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  97. Published

    Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model

    Berke, M. S., Fensholdt, L. K. D., Hestehave, Sara, Kalliokoski, Otto & Abelson, Klas, Jan 2022, In: PLoS ONE. 17, 1, 21 p., e0260356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. 2023
  99. Published

    In vivo effect of rFVIII and rFVIIa in hemophilia A rats evaluated by the Tail Vein Transection Bleeding Model

    Stagaard, Rikke, Øvlisen, Gabi Overgaard, Klæbel, J. H., Danielsen, D., Lund, A., Elm, T. & Ley, C. D., 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1189-1199 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    An increased weaning age and liquid feed enhances weight gain compared to piglets fed dry feed pre-weaning

    Lyderik, Kimmie Kyed, Madsen, Johannes Gulmann, Larsen, Christina, Pedersen, M. L. M., Kjeldsen, N. J., Williams, Andrew Richard, Hedemann, M. S. & Williams, Charlotte Amdi, 2023, In: Animal. 17, 5, 100801.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Antinociceptive effects of nortriptyline and desipramine hydrochloride in Speke's hinge-back tortoise (Kinixys Spekii)

    Musembi Makau, Christopher, Towett, P. K., Kanui, T. I. & Abelson, Klas, 2023, In: Fundamental and Clinical Pharmacology. 37, 3, p. 567-576

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Bovine colostrum as a fortifier to human milk in very preterm infants – A randomized controlled trial (FortiColos)

    Ahnfeldt, Agnethe May, Aunsholt, Lise, Hansen, Bo Mølholm, Hoest, B., Jóhannsdóttir, V., Kappel, S. S., Klamer, A., Möller, S., Moeller, B. K., Sangild, Per Torp, Skovgaard, A. L., van Hall, Gerrit, Vibede, L. D. & Zachariassen, G., 2023, In: Clinical Nutrition. 42, 5, p. 773-783 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis

    Pedersen, Kamilla, Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2023, In: Nutrients. 15, 2445.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Dietary non-starch polysaccharides impair immunity to enteric nematode infection

    Valente, Angela Hørdum, Jensen, K. M. R., Myhill, Laura Jessica, Zhu, L., Mentzel, Caroline M. Junker, Krych, Lukasz, Simonsen, H. T., Castro-Mejía, J. L., Gobbi, Alex, Bach Knudsen, K. E., Nielsen, Dennis Sandris, Thamsborg, Stig Milan & Williams, Andrew Richard, 2023, In: BMC Biology. 21, 16 p., 138.

    Research output: Contribution to journal › Journal article › Research › peer-review

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