The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. Published

    8-OH-DPAT Induces Compulsive-like Deficit in Spontaneous Alternation Behavior: Reversal by MDMA but Not Citalopram

    Odland, Anna Ulstein, Jessen, L., Fitzpatrick, C. M. & Andreasen T., Jesper, 2019, In: ACS Chemical Neuroscience. 10, 7, p. 3094-3100 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    In vivo effect of rFVIII and rFVIIa in hemophilia A rats evaluated by the Tail Vein Transection Bleeding Model

    Stagaard, Rikke, Øvlisen, Gabi Overgaard, Klæbel, J. H., Danielsen, D., Lund, A., Elm, T. & Ley, C. D., 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1189-1199 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    In vivo models of Escherichia coli infection in poultry

    Kromann, Sofie & Jensen, Henrik Elvang, 2022, In: Acta Veterinaria Scandinavica. 64, 33.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    A Gently Processed Skim Milk-Derived Whey Protein Concentrate for Infant Formula: Effects on Gut Development and Immunity in Preterm Pigs

    Aasmul-Olsen, Karoline, Akıllıoğlu, H. G., Christiansen, Line Iadsatian, Engholm-Keller, Kasper, Brunse, Anders, Stefanova, Denitsa Vladimirova, Bjørnshave, A., Bechshøft, M. R., Skovgaard, K., Thymann, Thomas, Sangild, Per Torp, Lund, Marianne N. & Bering, S. B., 2024, In: Molecular Nutrition and Food Research. 68, 6, 2300458.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A Novel Promazine Derivative Shows High in vitro and in vivo Antimicrobial Activity Against Staphylococcus aureus

    Ronco, T., Jørgensen, N. S., Holmer, I., Kromann, Sofie, Sheikhsamani, E., Permin, A., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Frontiers in Microbiology. 11, 12 p., 560798.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A Randomized, Controlled Study to Investigate How Bovine Colostrum Fortification of Human Milk Affects Bowel Habits in Preterm Infants (FortiColos Study)

    Kappel, S. S., Sangild, Per Torp, Ahnfeldt, Agnethe May, Johannsdottir, V., Soernsen, L. J., Bak, L. B., Friborg, C., Moller, S., Zachariassen, G. & Aunsholt, Lise, 2022, In: Nutrients. 14, 22, 14 p., 4756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A comparison of various methods of blood sampling in mice and rats: Effects on animal welfare

    Sreelatha, Harikrishnan Vijayakumar, Hansen, Axel Kornerup, Abelson, Klas & Sørensen, Dorte Bratbo, 2018, In: Laboratory Animals. 52, 3, p. 253-264

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A novel derivative of thioridazine shows low toxicity and efficient activity against gram‐positive pathogens

    Jørgensen, N. S., Saaby, Lasse, Andersson, A. M., Kromann, Sofie, Sheikhsamani, E., Permin, A., Ronco, T., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Antibiotics. 9, 6, 11 p., 327.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A novel technique to develop thoracic spinal laminectomy and a methodology to assess the functionality and welfare of the contusion spinal cord injury (SCI) rat model

    Sreelatha, Harikrishnan Vijayakumar, Krishnan, L. K. & Abelson, Klas, 2 Jul 2019, In: PLoS ONE. 14, 7, p. 1-19 19 p., e0219001.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study

    Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A reduced CP level without medicinal zinc oxide does not alter the intestinal morphology in weaned pigs 24 days post-weaning

    Larsen, Christina, Lynegaard, J. C., Pedersen, Anni Øyan, Kjeldsen, N. J., Hansen, C. F., Nielsen, Jens Peter & Williams, Charlotte Amdi, 2021, In: Animal. 15, 4, 100188.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A report on less-severe, long-duration persistent hind-limb ischemia surgical rabbit model

    Sreelatha, Harikrishnan Vijayakumar, Shenoy, S. J., Ranaraj, V. R., Sukhija, S. & Oloyo, A. K., 2021, In: Journal of the Hellenic Veterinary Medical Society. 72, 4, p. 3455-3462 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease

    Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree

    Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Alcohol-related breast cancer in postmenopausal women - effect of CYP19A1, PPARG and PPARGC1A polymorphisms on female sex-hormone levels and interaction with alcohol consumption and NSAID usage in a nested case-control study and a randomised controlled trial

    Kopp, T. I., Jensen, Ditte Marie, Ravn-Haren, G., Cohen, A., Sommer, H. M., Dragsted, Lars Ove, Tjønneland, A., Hougaard, D. M. & Vogel, U., 2016, In: BMC Cancer. 16, 19 p., 283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Alpha-Lactalbumin Enriched Whey Protein Concentrate to Improve Gut, Immunity and Brain Development in Preterm Pigs

    Nielsen, Charlotte Holme, Hui, Y., Nguyen, Duc Ninh, Ahnfeldt, Agnethe May, Burrin, D. G., Hartmann, Bolette, Heckmann, A. B., Sangild, Per Torp, Thymann, Thomas & Bering, S. B., 2020, In: Nutrients. 12, 1, 20 p., 245.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Moesgaard, S. G., Rasmussen, C. E., Zois, N. E., Falk, T., Reimann, Maria Josefine, Cirera, Susanna, Aupperle, H., Oyama, M. A. & Olsen, Lisbeth Høier, 19 Mar 2015, In: Research in Veterinary Science. 100, p. 197-206 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Amylopectin Chain Length Dynamics and Activity Signatures of Key Carbon Metabolic Enzymes Highlight Early Maturation as Culprit for Yield Reduction of Barley Endosperm Starch after Heat Stress

    Cuesta-Seijo, J. A., De Porcellinis, A. J., Valente, Angela Hørdum, Striebeck, A., Voss, C., Marri, L., Hansson, A., Jansson, A. M., Dinesen, M. H., Fangel, J. U., Harholt, J., Popovic, M., Thieme, M., Hochmuth, A., Zeeman, S. C., Mikkelsen, T. N., Jørgensen, R. B., Roitsch, Thomas Georg, Møller, Birger Lindberg & Braumann, I., 2019, In: Plant and Cell Physiology. 60, 12, p. 2692-2706 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

    Lindenberg, F. C., Lützhøft, Ditte Olsen, Krych, Lukasz, Fielden, J., Kot, Witold, Frøkiær, Hanne, van Galen, G., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Frontiers in Microbiology. 12, 666039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    An increased weaning age and liquid feed enhances weight gain compared to piglets fed dry feed pre-weaning

    Lyderik, Kimmie Kyed, Madsen, Johannes Gulmann, Larsen, Christina, Pedersen, M. L. M., Kjeldsen, N. J., Williams, Andrew Richard, Hedemann, M. S. & Williams, Charlotte Amdi, 2023, In: Animal. 17, 5, 100801.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease

    Meurs, K. M., Olsen, Lisbeth Høier, Reimann, Maria Josefine, Keene, B. W., Atkins, C. E., Adin, D., Aona, B., Condit, J., Defrancesco, T., Reina-Doreste, Y., Stern, J. A., Tou, S., Ward, J. & Woodruff, K., 2018, In: Pharmacogenetics and Genomics. 28, 2, p. 37-40 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Anthelmintic and metabolomic analyses of chicory (Cichorium intybus) identify an industrial by-product with potent in vitro antinematodal activity

    Peña-Espinoza, M., Valente, Angela Hørdum, Bornancin, L., Simonsen, H. T., Thamsborg, Stig Milan, Williams, Andrew Richard & López-Muñoz, R., 2020, In: Veterinary Parasitology. 280, 109088.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Anti-protozoal activity and metabolomic analyses of Cichorium intybus L. against Trypanosoma cruzi

    Peña-Espinoza, M., Romero-Uzqueda, Y., Valente, Angela Hørdum, de Roode, M., Simonsen, H. T., Thamsborg, Stig Milan, Williams, Andrew Richard & López-Muñoz, R., 2022, In: International Journal for Parasitology: Drugs and Drug Resistance. 20, p. 43-53 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Anti-protozoal activity of extracts from chicory (Cichorium intybus) against Cryptosporidium parvum in cell culture

    Woolsey, I. D., Valente, Angela Hørdum, Williams, Andrew Richard, Thamsborg, Stig Milan, Simonsen, H. T. & Enemark, H. L., 2019, In: Scientific Reports. 9, 1, 9 p., 20414.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Antibiotic Resistance of Lactobacillus spp. and Streptococcus thermophilus Isolated from Chinese Fermented Milk Products

    Li, Y., Li, L., Kromann, Sofie, Chen, M., Shi, L. & Meng, H., 2019, In: Foodborne pathogens and disease. 16, 3, p. 221-228

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Antinociceptive effects of nortriptyline and desipramine hydrochloride in Speke's hinge-back tortoise (Kinixys Spekii)

    Musembi Makau, Christopher, Towett, P. K., Kanui, T. I. & Abelson, Klas, 2023, In: Fundamental and Clinical Pharmacology. 37, 3, p. 567-576

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review

    Peña-Espinoza, M., Valente, Angela Hørdum, Thamsborg, Stig Milan, Simonsen, H. T., Boas, U., Enemark, H. L., López-Muñoz, R. & Williams, Andrew Richard, 22 Aug 2018, In: Parasites & Vectors. 11, 14 p., 475.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Antipsychotic medication and remission of psychotic symptoms 10 years after a first-episode psychosis

    Wils, Regitze Sølling, Gotfredsen, D. R., Hjorthøj, C., Austin, Stephen Fitzgerald, Albert, N., Secher, R. G., Thorup, Anne, Mors, O. & Nordentoft, Merete, 2017, In: Schizophrenia Research. 182, p. 42-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Applications of the comet assay in particle toxicology: air pollution and engineered nanomaterials exposure

    Møller, Peter, Hemmingsen, J. G., Jensen, Ditte Marie, Danielsen, P. H., Karottki, D. G., Jantzen, K., Roursgaard, Martin, Cao, Y., Kermanizadeh, A., Klingberg, H., Christophersen, D. V., Hersoug, L. & Loft, Steffen, 2015, In: Mutagenesis. 30, 1, p. 67-83 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Assessment of automated assays for serum amyloid A, haptoglobin (PIT54) and basic biochemistry in broiler breeders experimentally infected with Escherichia coli

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2022, In: Veterinary Research. 53, 1, 7 p., 25.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Assessment of evidence for nanosized titanium dioxide-generated DNA strand breaks and oxidatively damaged DNA in cells and animal models

    Møller, Peter, Jensen, Ditte Marie, Wils, Regitze Sølling, Guerra Andersen, M. H., Danielsen, P. H. & Roursgaard, Martin, 2017, In: Nanotoxicology. 11, 9-10, p. 1237-1256 20 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials

    Møller, Peter, Christophersen, D. V., Raun Jacobsen, N., Skovmand, A., Gouveia, A. C. D., Guerra Andersen, M. H., Kermanizadeh, A., Jensen, Ditte Marie, Danielsen, P. H., Roursgaard, Martin, Jantzen, K. & Loft, Steffen, May 2016, In: Critical Reviews in Toxicology. 46, 5, p. 437-476 40 p.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model

    Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Betamethasone Treatment for Atopic Dermatitis in Gut Microbiota Transplanted Mice

    Debes, Karina Poulsdóttir, Evdina, N. A., Laigaard, A., Larsen, J. M., Zachariassen, L. F., Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2020, In: Comparative Medicine. 70, 1, p. 6-15 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors

    Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Bodyweight, locomotion, and behavioral responses in the naked mole-rat (heterocephalus glaber) after lipopolysaccharide administration

    Kisipan, Mosiany Letura, Ojoo, R. O., Kanui, T. I. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 191-191 PE21.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  37. Published

    Bovine colostrum as a fortifier to human milk in very preterm infants – A randomized controlled trial (FortiColos)

    Ahnfeldt, Agnethe May, Aunsholt, Lise, Hansen, Bo Mølholm, Hoest, B., Jóhannsdóttir, V., Kappel, S. S., Klamer, A., Möller, S., Moeller, B. K., Sangild, Per Torp, Skovgaard, A. L., van Hall, Gerrit, Vibede, L. D. & Zachariassen, G., 2023, In: Clinical Nutrition. 42, 5, p. 773-783 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Brain Barrier Disruption and Region-Specific Neuronal Degeneration during Necrotizing Enterocolitis in Preterm Pigs

    Brunse, Anders, Abbaspour, A. & Sangild, Per Torp, 1 Oct 2018, In: Developmental Neuroscience. 40, 3, p. 198–208

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets

    Henriksen, Nicole Lind, Asmussen, K. S., Pan, X., Jiang, Pingping, Mori, Yuki, Christiansen, Line Iadsatian, Sprenger, R. R., Ejsing, C. S., Pankratova, Stanislava & Thymann, Thomas, 2022, In: Scientific Reports. 12, 1, 3303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8-to 10-Year Period

    Birkegård, A. C., Reimann, Maria Josefine, Martinussen, Torben, Haggstrom, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2016, In: Journal of Veterinary Internal Medicine. 30, 1, p. 63-68 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Buprenorphine alleviation of pain does not compromise the rat monoarthritic pain model

    Berke, M. S. & Abelson, Klas, 2017, In: Scandinavian Journal of Pain. 16, p. 167-167 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  42. Published

    CEREBROSPINAL FLUID FROM PRETERM PIGS WITH NECROTIZING ENTEROCOLITIS HAS ALTERED CYTOKINE PROFILE AND PROMOTES HIPPOCAMPAL NEURITOGENESIS

    Pankratova, Stanislava, Sun, Jing, Li, Y. & Sangild, Per Torp, Nov 2016, In: European Journal of Pediatrics. 175, 11, p. 1688-1688 1 p., EAPS-0806.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  43. Published

    CTLA4-Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats

    Øvlisen, Gabi Overgaard, Thygesen, P., Weldingh, K. N., Bloem, E., Skov, Søren, Almholt, K., Lövgren, K. M., Ley, C. D. & Holm, T. L., 2022, In: Haemophilia. 28, 4, p. 568-577

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Cardiovascular of Inflammatory Disease Models: In vivo imaging, Pathology and Pharmacology

    Olsen, Lisbeth Høier, Nielsen, O. L., Hunter, I., Falk, B. T., Cremer, Signe Emilie, Ludvigsen, Trine Pagh, Reimann, Maria Josefine, Olsen, H. G., Nielsen, K. M., Laursen, H., Kronborg, S. & Kjempff, C. T., 2014.

    Research output: Contribution to conference › Poster › Communication

  45. Published

    Central control of energy balance by amylin and calcitonin receptor agonists and their potential for treatment of metabolic diseases

    Zakariassen, Hannah Louise, John, L. M. & Lutz, T. A., 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 3, p. 163-177

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Chronic dyslipidemia induces fatty liver disease in Guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    Clinical outcome and gut development after insulin-like growth factor-1 supplementation to preterm pigs

    Holgersen, Kristine, Rasmussen, Martin Bo, Carey, G., Burrin, D. G., Thymann, Thomas & Sangild, Per Torp, 2022, In: Frontiers in Pediatrics. 10, 868911.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels

    Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Colibacillosis in poultry: Aetiology, pathogenesis, diagnosis, and control

    Kromann, Sofie, 2022, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  50. Published

    Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs

    Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.

    Research output: Contribution to journal › Journal article › Research › peer-review

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