The Graduate Programme for In Vivo Pharmacology and Experimental Animals

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  1. Published

    Creatine kinase response to high-intensity aerobic exercise in adult-onset muscular dystrophy

    Andersen, S. P., Sveen, M., Wils, Regitze Sølling, Madsen, K. L., Hansen, J. B., Madsen, M. L. & Vissing, John, 2013, In: Muscle & Nerve. 48, 6, p. 897-901 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin

    Henriksen, Nicole Lind, Aasmul-Olsen, Karoline, Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Mullertz, Anette , Sangild, Per Torp, Bering, S. B. & Thymann, Thomas, 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction

    Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  4. Published

    Decreased Right Ventricular Systolic Function in Dogs with Myxomatous Mitral Valve Disease

    Olsen, Lisbeth Høier, Reimann, Maria Josefine, Møller, J. E., Häggström, J., Jangdin, S. E., Falk, B. T., Uggla, T. & Zois, N. E., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 628-629 2 p., C6.

    Research output: Contribution to journal › Conference abstract in journal › Research

  5. Published

    Decreased expression of the GLP-1 receptor after segmental artery injury in mice

    Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Brockhoff, P. M. B., Seested, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2019, In: Obesity Science & Practice. 5, 3, p. 281-288

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

    Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Development of an aerogenous Escherichia coli infection model in adult broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Scientific Reports. 11, 15 p., 19556.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Diet Modulates the High Sensitivity to Systemic Infection in Newborn Preterm Pigs

    Bæk, Ole, Brunse, Anders, Nguyen, Duc Ninh, Moodley, Arshnee, Thymann, Thomas & Sangild, Per Torp, 2020, In: Frontiers in Immunology. 11, 14 p., 1019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Diet composition drives tissue-specific intensity of murine enteric infections

    Israelson, H., Vedsted-Jakobsen, Amalie, Zhu, L., Gagnaire, A., von Münchow, Alexandra, Polakovicova, N., Valente, Angela Hørdum, Raza, Ali, Andersen-Civil, A. I. S., Olsen, John Elmerdahl, Myhill, Laura Jessica, Geldhof, P. & Williams, Andrew Richard, 2024, In: mBio. 15, 2, 22 p., e0260323.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation

    Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis

    Pedersen, Kamilla, Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2023, In: Nutrients. 15, 2445.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats

    Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Dietary non-starch polysaccharides impair immunity to enteric nematode infection

    Valente, Angela Hørdum, Jensen, K. M. R., Myhill, Laura Jessica, Zhu, L., Mentzel, Caroline M. Junker, Krych, Lukasz, Simonsen, H. T., Castro-Mejía, J. L., Gobbi, Alex, Bach Knudsen, K. E., Nielsen, Dennis Sandris, Thamsborg, Stig Milan & Williams, Andrew Richard, 2023, In: BMC Biology. 21, 16 p., 138.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Dietary seaweed (Saccharina latissima) supplementation in pigs induces localized immunomodulatory effects and minor gut microbiota changes during intestinal helminth infection

    Bonde, C. S., Mejer, Helena, Myhill, Laura Jessica, Zhu, L., Jensen, Penille, Büdeyri Gökgöz, Nilay, Krych, Lukasz, Nielsen, Dennis Sandris, Skovgaard, K., Thamsborg, Stig Milan & Williams, Andrew Richard, 2023, In: Scientific Reports. 13, 16 p., 21931.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis

    Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Does vitamin C deficiency promote fatty liver disease development?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Donor-dependent fecal microbiota transplantation efficacy against necrotizing enterocolitis in preterm pigs

    Hui, Y., Vestergaard, G., Deng, Ling, Kot, Witold, Thymann, Thomas, Brunse, Anders & Nielsen, Dennis Sandris, 2022, In: npj Biofilms and Microbiomes. 8, 1, 12 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Dramatic increase in slaughter condemnations due to Escherichia coli ST23 and ST101 within the Danish broiler production

    Kromann, Sofie, Baig, S., Olsen, Rikke Heidemann, Edslev, S. M., Thoefner, Ida , Bojesen, Anders Miki, Jensen, Henrik Elvang & Stegger, M., 2023, In: Veterinary Microbiology. 280, 109696.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Dyslipidemia: Obese or Not Obese-That Is Not the Question

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    EARLY ENTERAL FEEDING REDUCES SEPSIS RESPONSE AND NEUROINFLAMMATION IN A PIG MODEL OF NEONATAL BLOODSTREAM INFECTION

    Brunse, Anders, Worsøe, P. S., Pors, S. E., Skovgaard, K. & Sangild, Per Torp, Nov 2016, In: European Journal of Pediatrics. 175, 11, p. 1497-1497 1 p., 307, EAPS-0930.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. Published

    Effect of the sodium-glucose cotransporter-2 inhibitor dapagliflozinon platelet aggregation response in Cavalier King Charles Spanielswith and without cardiac disease

    Speitzer, A., Øgelund, E., Reimann, Maria Josefine, Møller, J. E., Skovsted, G. F., Lyhne, Mille Kronborg, Verma, S., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 2473 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    Effects of Transdermal Fentanyl Treatment on Acute Pain and Inflammation in Rats with Adjuvant-induced Monoarthritis

    Berke, M. S., Colding-Jørgensen, Pernille, Pedersen, L. G., Hestehave, Sara, Kalliokoski, Otto, Jensen, Henrik Elvang, Sørensen, Dorte Bratbo, Hau, Jann & Abelson, Klas, 2022, In: Comparative Medicine. 72, 5, p. 320–329 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Effects of Weaning Age and Creep Feed Type on Growth Performance and Gut Maturation in Weaned Piglets

    Lyderik, Kimmie Kyed, Zhang, X., Larsen, Christina, Kjeldsen, N. J., Pedersen, M. L. M., Hedemann, M. S., Williams, Andrew Richard, Williams, Charlotte Amdi & Madsen, Johannes Gulmann, 2023, In: Animals. 13, 11, 1851.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Effects of anti-inflammatory drugs on induced chronic Inflammation in the naked mole rat

    Thuo, Jesse Kevin Ndung´u, Towett, P., Kanui, T. I. & Abelson, Klas, 2022, In: Laboratory Animals. 56, S1, p. 131-132 PA24.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  27. Published

    Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model

    Berke, M. S., Fensholdt, L. K. D., Hestehave, Sara, Kalliokoski, Otto & Abelson, Klas, Jan 2022, In: PLoS ONE. 17, 1, 21 p., e0260356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Effects of early postnatal gastric and colonic microbiota transplantation on piglet gut health

    Larsen, Christina, Offersen, Simone Margaard, Brunse, Anders, Pirolo, Mattia, Kar, S. K., Guadabassi, L. & Thymann, Thomas, 2023, In: Journal of Animal Science and Biotechnology. 14, 14 p., 158.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Effects of exercise and dietary protein sources on adiposity and insulin sensitivity in obese mice

    Fjære, E., Myrmel, L. S., Lützhøft, Ditte Olsen, Andersen, H., Holm, J. B., Kiilerich, P., Hannisdal, R., Liaset, B., Kristiansen, Karsten & Madsen, L., 2019, In: Journal of Nutritional Biochemistry. 66, p. 98-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Effects of inhibition of Nav1.3, Nav1.7, and Nav1.8 channels on pain-related behavior in Speke's hinge-back tortoise (Kinixys spekii)

    Musembi Makau, Christopher, Towett, P. K., Kanui, T. I. & Abelson, Klas, 2024, In: Journal of Neuroscience Research. 102, 1, e25274.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

    Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Electrocardiography and heart rate variability in Göttingen Minipigs: Impact of diurnal variation, lead placement, repeatability and streptozotocin-induced diabetes

    Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Helgogaard, T., Vegge, A., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 107221.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Elevated levels of circulating cell-free DNA and neutrophil proteins are associated with neonatal sepsis and necrotizing enterocolitis in immature mice, pigs and infants

    Nguyen, Duc Ninh, Stensballe, A., Lai, J. C. Y., Jiang, Pingping, Brunse, Anders, Li, Y., Sun, Jing, Mallard, C., Skeath, T., Embleton, N. D., Berrington, J. E. & Sangild, Per Torp, 2017, In: Innate Immunity. 23, 6, p. 524-536 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Empirical study of bias in a rat model of rheumatoid arthritis (RA)

    Seveljevic-Jaran, Dasa, Hau, Jann, Abelson, Klas & Kalliokoski, Otto, 2022, University of Copenhagen. 91 p.

    Research output: Book/Report › Ph.D. thesis › Research

  35. Published

    Enteral broad-spectrum antibiotics antagonize the effect of fecal microbiota transplantation in preterm pigs

    Brunse, Anders, Offersen, Simone Margaard, Mosegaard, J. J., Deng, Ling, Damborg, Peter Panduro, Nielsen, Dennis Sandris, Sangild, Per Torp, Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Gut Microbes. 13, 1, p. 1-16 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Establishment and application of an aerogenous model of avian colibacillosis

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Thoefner, Ida & Jensen, Henrik Elvang, 2023.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  37. Published

    Evaluation of the breeding program aiming at reducing the prevalence of myxomatous mitral valve disease in Cavalier King Charles Spaniels in Denmark

    Birkegaard , A. C., Reimann, Maria Josefine, Häggström, J., Martinussen, Torben, Pedersen , H. D. & Olsen, Lisbeth Høier, 2013, American College of Veterinary Internal Medicine, Congress Proceedings. Sellon, R. K. & McClure, J. T. (eds.). Lakewood, p. 172 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  38. Published

    Extracellular vesicles as drivers of non-alcoholic fatty liver disease: Small particles with big impact

    Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 1, p. 1-13 13 p., 93.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    FECAL MICROBIOTA TRANSPLANTATION PROTECTS AGAINST NECROTIZING ENTEROCOLITIS BUT INCREASES OVERALL MORTALITY IN PRETERM NEWBORN PIGS

    Brunse, Anders, Martin, L., Cilieborg, Malene Skovsted, Christensen, Lars, Thymann, Thomas, Pieper, R. & Sangild, Per Torp, Nov 2016, In: European Journal of Pediatrics. 175, 11, p. 1731-1732 2 p., 922 EAPS-0605.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Seested, T., Gram-Nielsen, S., Kristensen, N. R. & Refsgaard, H., 2018, In: Journal of Diabetes Research. 2018, 17 p., 1205121.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Fat and carbohydrate metabolism during exercise in late-onset Pompe disease

    Preisler, N., Laforet, P., Madsen, K. L., Wils, Regitze Sølling, Lukacs, Z., Ørngreen, M. C., Lacour, A. & Vissing, John, 2012, In: Molecular Genetics and Metabolism. 107, 3, p. 462-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Fecal filtrate transplantation protects against necrotizing enterocolitis

    Brunse, Anders, Deng, Ling, Pan, X., Hui, Y., Castro Mejia, J. L., Kot, Witold, Nguyen, Duc Ninh, Secher, Jan Bojsen-Møller, Nielsen, Dennis Sandris & Thymann, Thomas, 2022, In: The ISME Journal. 16, p. 686–694

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice

    Rasmussen, Torben Sølbeck, Mentzel, Caroline M. Junker, Danielsen, M. R., Jakobsen, Rasmus Riemer, Zachariassen, L. S. F., Castro Mejia, J. L., Brunse, Anders, Hansen, Lars Hestbjerg, Hansen, Camilla Hartmann Friis, Hansen, Axel Kornerup & Nielsen, Dennis Sandris, 2023, In: Gut Microbes. 15, 1, 21 p., 2208504.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Fibrous dysplasia animal models: A systematic review

    Hopkins, Chelsea, de Castro, L. F., Corsi, A., Boyce, A., Collins, M. T., Riminucci, M. & Heegaard, Anne-Marie, 2022, In: Bone. 155, 13 p., 116270.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Fighting Irreproducibility in Preclinical Neuroscience Using a Meta-analytical Approach: The Case of the Chronic Unpredictable Stress Model of Depression

    Berrio Sanchez, Jenny Paola, Kalliokoski, Otto & Hau, Jann, 2023, University of Copenhagen. 80 p.

    Research output: Book/Report › Ph.D. thesis › Research

  46. Published

    Finding new analgesics: Computational pharmacology faces drug discovery challenges

    Barakat, Ahmed, Munro, G. & Heegaard, Anne-Marie, 2024, In: Biochemical Pharmacology. 222, 21 p., 116091.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Porsgaard, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 6, p. 783-794

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    FortiColos - A multicentre study using bovine colostrum as a fortifier to human milk in very preterm infants: Study protocol for a randomised controlled pilot trial

    Ahnfeldt, Agnethe May, Hyldig, N., Li, Y., Kappel, S. S., Aunsholdt, L., Sangild, Per Torp & Zachariassen, G., 2019, In: Trials. 20, 9 p., 279.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Gabor patterns as stimuli in a rodent visual attention task

    Caballero-Puntiverio, M., Prichardt, S., Klem, Louise Bomholt, Bundesen, C., Vangkilde, Signe & Andreasen T., Jesper, 2020, In: Neuroscience Letters. 728, 8 p., 134970.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology

    Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.

    Research output: Contribution to journal › Journal article › Research › peer-review

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